Table 2 Levels of evidence for determining the quality of the study design
Domains | ||
|---|---|---|
Levels of Evidence (LoE) | Wound healing Offloading | Surgical procedures from wound healing domain, PAD, secondary prevention, organization of care |
Level 1 | Systematic reviews of randomized controlled trials (RCTs), with or without meta-analysis | |
Level 2 | Randomized controlled trials Systematic reviews of a combination of RCTs and non-randomized controlled studies, or non-randomized controlled studies only, with or without meta-analysis | |
Level 3 | Not included | Non-randomized controlled studies: Controlled before-after studies, Interrupted Time-series, prospective cohort studies, retrospective cohort studies (propensity score matched, regression technique) |