Table 1 Framework and search strategy for analyses

 Population

Patients with asthma

Asthma

Asthma

 Intervention

N/A

N/A

N/A

 Comparator

N/A

N/A

N/A

 Outcome

Factors that are likely to affect asthma control

Adherence, compliance, education, dosing frequency inhaler, age, lifestyle, gender, comorbidities

Adherence, compliance, education, dosing frequency, inhaler, age, lifestyle, gender, comorbidities

 Setting

Gulf Cooperation Council countries

Bahrain, Kuwait, Oman, Qatar, Saudi Arabia and United Arab Emirates

Bahrain, Kuwait, Oman, Qatar, Saudi Arabia and United Arab Emirates

 LANGUAGE LIMIT

–

EMBASE: English language

PubMed: None

EMBASE: English language

PubMed: None

 TIME LIMIT

–

None

EMBASE: Published between 2018 and 2019

PubMed: Publication between 2018/01/01 and 2019/11/04

 Other LIMITS

EMBASE: Studies in humans, publications with abstract.

PubMed: None

EMBASE: Studies in humans, publications with abstract

PubMed: None

 Population

Patients with asthma

Asthma

Asthma

 Intervention

ICS/LABA

Corticosteroid AND long AND acting AND agonist

 Comparator

N/A

 Outcome

Include all measures of asthma control in the literature

[No term was adopted as it was deemed more appropriate to consider in search screening than to limit by term]

[No term was adopted as it was deemed more appropriate to consider in search screening than to limit by term]

 Setting

N/A

 Study design

All study types that may be used in effectiveness research

Effectiveness studies, real world studies, real life, cohort analysis, retrospective studies, database studies

RCTs, Randomised Control Trials, effectiveness studies, real world evidence, real life studies, real world data, real world studies

 LANGUAGE LIMIT

English language

Database limit: English language

Database limit: English language

 TIME LIMIT

NONE

January 2018

January 2018 – November 2019

 Other LIMITS

Human studies: randomised controlled trial, systematic review