Table 3 Cox Regression Analysis of Association between Clinical Risk Factors and Incidence of Hypertension

Male

1.14 (0.80, 1.62)

0.47

Age (per year increase)

1.04 (1.03, 1.05)

< 0.001

1.02 (1.00, 1.03)

0.06

BMI (per kg/m²increase)

1.09 (1.04, 1.14)

< 0.001

1.07 (1.01, 1.13)

0.02

Han ethnicity

1.27 (0.80, 2.02)

0.32

Current smoking

0.84 (0.59, 1.21)

0.35

Current alcohol use

0.83 (0.58, 1.18)

0.30

eGFR (per ml/min increase)

0.99 (0.98, 1.00)

< 0.01

NA

NA

Diabetes

1.19 (0.61, 2.32)

0.62

TC > 5.2 (mmol/l)

1.24 (0.79, 1.96)

0.36

TG > 1.7 (mmol/l)

1.18 (0.86, 1.63)

0.31

HDL-c < 1.0 (mmol/l)

1.22 (0.90, 1.67)

0.20

LDL-c > 4.1(mmol/l)

1.42 (0.45, 4.45)

0.55

Dyslipidemia

1.28 (0.95, 1.73)

0.11

HBs Ag+

1.16 (0.74, 1.82)

0.51

HCV-Ab+

1.69 (1.05, 2.72)

0.03

NA

NA

Route of HIV transmission

NA

NA

 Heterosexual

0.99 (0.55, 1.80)

0.98

 MSM

1.21 (0.67, 2.17)

0.53

 Blood transfusion

4.12 (2.08, 8.19)

< 0.001

 Others

Reference

Years since HIV diagnosis

(per year increase)

1.06 (0.97, 1.14)

0.19

Baseline CD4+ cell count

(per cells/mm³increase)

0.999 (0.997, 1.000)

0.03

1.003 (1.001, 1.004)

< 0.01

Baseline HIV Viral load

(per log10 copies/ml increase)

0.97 (0.74, 1.27)

0.82

Stavudine exposure

1.92 (1.42, 2.60)

< 0.001

NA

NA

Zidovudine exposure

0.50 (0.36, 0.71)

< 0.001

0.15 (0.10, 0.24)

< 0.001

TDF exposure

0.46 (0.33, 0.64)

< 0.001

0.13 (0.08, 0.21)

< 0.001

Recent CD4+ cell count

(per cells/mm³increase)

0.996 (0.995, 0.997)

< 0.001

Recent CD4+/CD8+ ratio

0.09 (0.05, 0.17)

< 0.001

0.14 (0.06, 0.31)

< 0.001

Recent VL

(per log10 copies/ml increase)

1.87 (1.65, 2.12)

< 0.001

1.28 (1.08, 1.51)

< 0.01