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Table 2 Hazard ratios (HR) and 95% confidence interval (CI) of haemoglobin trajectory classes on incident stroke in the total, men and women

From: Trajectories of Haemoglobin and incident stroke risk: a longitudinal cohort study

 

Model 1

 

Model 2

 

HR (95% CI)

P-value

HR (95% CI)

P-value

Total

 Normal-stable

Reference

 

Reference

 

 High-stable, HR (95% CI)

1.53 (1.07, 2.20)

0.020

1.23 (0.77, 1.97)

0.394

 Decreasing, HR (95% CI)

1.85 (0.98, 3.49)

0.056

2.94 (1.22, 7.06)

0.016

Men

 Normal-stable

Reference

 

Reference

 

 High-stable, HR (95% CI)

1.71 (1.14, 2.58)

0.010

1.26 (0.75, 2.11)

0.376

 Decreasing, HR (95% CI)

2.99 (1.07, 8.36)

0.037

4.12 (1.50, 11.28)

0.006

Women

 Normal-stable

Reference

 

Reference

 

 High-stable, HR (95% CI)

1.15 (0.52, 2.56)

0.724

1.08 (0.34, 3.49)

0.893

 Decreasing, HR (95% CI)

2.43 (0.96, 6.16)

0.061

1.66 (0.34, 8.19)

0.534

  1. HR hazard ratio, CI confidence interval;
  2. † Unadjusted model
  3. ‡ Adjusting for baseline age, sex (only for total), smoker, drinker, GFR, BMI, diabetes mellitus, hypertension, and dyslipidemia