Fig. 4

Minimum detectable RR for risk factors (RR ≥1) for five incidence rates. The minimum detectable relative risk (RR) has been estimated for five incidence rates (0.1%, 1%, 5%, 10%, 25%) and a range of an exposed fraction of the MATEX cohort between 1 and 30%. The red area describes RRs not detectable within reasonable exposure prevalence and disease incidence, the yellow area describes RRs possibly detectable depending on exposure prevalence and/or disease incidence, and the green area describes the RRs which can be detected in whole range of exposure prevalence and disease incidence. A study power of 90% has been assumed