Table 1 Baseline characteristics, number of first events according to BMI category and in all participants, and hazard ratios for LRE for potential confounders (continuousa and categoricalb variables)
Characteristic | BMI category (kg/m2) | All participants | Hazard ratio (95% confidence intervals) | ||
|---|---|---|---|---|---|
<25 | 25 - < 30 | ≥30 | |||
Total, n (%) | 42,452 (44.6) | 35,073 (36.9) | 17,601 (18.5) | 95,126 | Â |
Recruitment age, median (years) | 60.0 (50–74) | 61.0 (50–74) | 60.0 (50–74) | 60.0 (50–74) | 1.01a (0.99–1.02) |
Smoker, n (%) | 14,740 (34.7) | 12,616 (36.0) | 6621 (37.6) | 33,977 (35.7) | 1.89b (1.52–2.35) |
Hypertension, n (%) | 9477 (22.3) | 12,116 (34.5) | 8440 (48.0) | 30,033 (31.6) | 1.38b (1.11–1.73) |
Heart disease, n (%) | 1721 (4.1) | 2086 (5.9) | 1416 (8.0) | 5223 (5.5) | 2.17b (1.53–3.06) |
Hypercholesterolemia, n (%) | 8001 (18.8) | 9148 (26.1) | 5440 (30.9) | 22,589 (23.7) | 1.68b (1.33–2.11) |
Diabetes, n (%) | 836 (2.0) | 1689 (2.6) | 2263 (12.9) | 4788 (5.0) | 2.76b (1.99–3.83) |
IMD, mean | 17.0 | 18.7 | 21.3 | 18.5 | 1.09a (1.01–1.03) |
Alcohol consumption (units/week) | |||||
 None | 8479 (20.0) | 8189 (23.3) | 5547 (31.5) | 22,215 (23.4) | 1b (reference) |
  < 1–15 | 31,811 (74.9) | 25,324 (72.2) | 11,473 (65.2) | 68,608 (72.1) | 0.64b (0.51–0.82) |
 16–20 | 1448 (3.4) | 1067 (3.0) | 366 (2.1) | 2881 (3.0) | 0.82b (0.44–1.53) |
  ≥ 21 | 714 (1.7) | 493 (1.4) | 215 (1.2) | 1422 (1.5) | 1.66b (0.89–3.09) |
Alcohol consumption (units/week) | Number of first LREs | Â | |||
 None | 23 | 36 | 42 | 101 |  |
  < 1–15 | 71 | 77 | 55 | 202 |  |
 16–20 | 17 | 10 | 3 | 11 |  |
  ≥ 21 | 4 | 5 | 2 | 11 |  |
 Total | 102 | 123 | 100 | 325 |  |