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Table 9 Exhaled breath biomarker summary and statistical comparisons

From: Reductions in biomarkers of exposure, impacts on smoking urge and assessment of product use and tolerability in adult smokers following partial or complete substitution of cigarettes with electronic cigarettes

 

Exclusive e-Cigarette use groups

Dual use groups

Nicotine cessation

N = 13

Biomarker

Tobacco rechargeable

N = 15

Cherry rechargeable

N = 13

Cherry disposable

N = 13

Tobacco rechargeable

N = 14

Cherry rechargeable

N = 15

Cherry disposable

N = 13

CO (ppm)

      

 Day −1

27.2 ± 10.5

27.3 ± 6.9

26.9 ± 6.4

25.1 ± 7.3

25.4 ± 7.7

24.7 ± 5.5

29.3 ± 10.4

 Day 5

2.9 ± 0.8

2.9 ± 0.8

2.7 ± 0.9

17.3 ± 5.7

16.1 ± 3.3

18.2 ± 5.7

2.8 ± 0.7

 p-value Day −1 vs Day 5

<0.0001

<0.0001

<0.0001

0.0021

<0.0001

0.0002

<0.0001

 p-value Day 5 vs Cessation

0.7990

0.8033

0.9109

<0.0001

<0.0001

<0.0001

NA

NO (ppb)

      

 Day −1

14.8 ± 12.8

11.5 ± 4.8

10.0 ± 4.0

14.9 ± 11.1

10.6 ± 4.6

14.3 ± 13.5

11.3 ± 4.0

 Day 5

23.3 ± 21.6

15.5 ± 9.0

14.3 ± 6.5

12.9 ± 6.3

10.7 ± 4.4

11.4 ± 6.0

16.8 ± 10.1

 p-value Day −1 vs Day 5

0.0075

0.1325

0.0053

0.3118

0.9415

0.3287

0.0321

 p-value Day 5 vs Cessation

0.2370

0.6031

0.5674

0.0313

0.0615

0.0119

NA

  1. Values are presented as mean ± SD