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Table 2 Observed and expected cancers among the HIV-infected patients as compared to the general population

From: Cancer incidence and mortality for all causes in HIV-infected patients over a quarter century: a multicentre cohort study

Observational-time

1986-2009

Cancer type or site (ICD-10)

Observed (n)

Expected (n)

SIR (95% CI)

AIDS-defining-cancer

Kaposi’s sarcoma (C46)

287

1.7

168.5 (149.6-189.2)

Cervix Uteri (C53)^

41

2.3

17.9 (12.8-24.2)

Non-Hodgkin lymphoma (C82-5, C96)

313

12.8

24.5 (21.8-27.3)

Non-AIDS-defining-cancer

Tongue and lingual tonsil (C01-C02)

5

0.2

22.1 (7.1-51.5)

Stomach (C16)

9

6.5

1.4 (0.6-2.6)

Colon (C18)

32

14.2

2.2 (1.5-3.2)

Rectum-Anus (C19-21)

24

7.7

3.1 (2.0-4.7)

Liver, primary (C22)

61

5.8

10.6 (8.1-13.6)

Larynx (C32)

9

3.3

2.8 (1.3-5.3)

Lung, bronchus and trachea (C33-34)

29

19.5

1.5 (1.0-2.1)

Melanoma (C43)

14

12.9

1.1 (0.6-1.8)

Breast (C50)

32

24.7

1.3 (0.9-1.8)

Vagina and vulva (C51-52, 57)

5

0.2

22.1 (7.1-51.5)

Penis (C60)

8

0.3

28.0 (12.1-55.2)

Prostate (C61)

8

16.2

0.5 (0.3-1.0)

Testis (C62)

19

7.9

2.4 (1.4-3.7)

Kidney (C64-66, C68)

9

8.9

1.0 (0.5-1.9)

Bladder (C67)

6

13.4

0.4 (0.2-1.0)

Brain and CNS (C70-72)

4

6

0.7 (0.2-1.7)

Thyroid (C73)

7

11.3

0.6 (0.2-1.3)

Hodgkin lymphoma (C81)

59

5

11.8 (9.0-15.2)

Myeloid leukaemia (C92)

4

2.7

1.5 (0.4-3.7)

  1. ^Cervix uteri was included in AIDS-defining-cancer after 1993. In bold are reported cancers with statistical significant SIRs (p < 0.05). We did not performed SIR for cancers with less than 4 cases.
  2. Abbreviations: ICD international classification of diseases, SIR standardized incidence ratio, 95% CI 95% confidence interval.