Prevention of type 2 diabetes in adults with impaired glucose tolerance: the European Diabetes Prevention RCT in Newcastle upon Tyne, UK

Table 3 Relationship between sustained change* in secondary outcomes and progression to T2D by trial group.

	Number in intervention group (%)	Number in control group (%)	Total number (%)	Number of cases of T2D over five years follow-up
Body weight
Sustained beneficial change	23 (45)	24 (47)	47 (46)	3
No sustained beneficial change	28 (55)	27 (53)	55 (54)	13
Physical activity score
Sustained beneficial change	18 (35)	19 (37)	37 (36)	2
No sustained beneficial change	33 (65)	32 (63)	65 (64)	14
Intake of dietary fibre
Sustained beneficial change	15 (29)	15 (29)	30 (29)	3
No sustained beneficial change	36 (71)	36 (71)	72 (71)	13
% energy intake from fat
Sustained beneficial change	21 (41)	21 (41)	42 (41)	3
No sustained beneficial change	30 (59)	30 (59)	60 (59)	13
% energy intake from carbohydrate
Sustained beneficial change	15 (29)	16 (31)	31 (30)	2
No sustained beneficial change	36 (71)	35 (69)	71 (70)	14

* Sustained beneficial change in secondary outcome measures was defined as: a beneficial change (>0.01 units) maintained for two or more years (i.e. weight loss, reduction in % energy intake from fat, increase in % intake from carbohydrate, increase in intake of dietary fibre and increase in physical activity score).

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