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Table 2 Measures used at the screening phase (2001–06) and at the health assessment (2009–11) in the ADDITION-PRO study

From: Protocol for ADDITION-PRO: a longitudinal cohort study of the cardiovascular experience of individuals at high risk for diabetes recruited from Danish primary care

 

Screening phase: low risk1participants

Screening phase: high risk2participants

ADDITION-PROhealth assessment

Danish risk score questionnaire

X

X

X

Socio-demographic variables

Age

X

X

X

Sex

X

X

X

Biochemistry

Random capillary blood glucose

 

X

 

Fasting capillary blood glucose3

 

X

 

Venous glycated haemoglobin (HbA1c)

 

X

X

75 g oral glucose tolerance test3,4

 

X

X

Insulin

  

X

Total cholesterol

 

X

X

LDL-cholesterol

 

X

X

HDL-cholesterol

 

X

X

Triglycerides

 

X

X

Plasma and urine creatinine3

 

X

X

Urine albumin3

 

X

X

DNA3

 

X

X

Alanine transaminase

  

X

Alkaline phosphatase

  

X

Biobank: plasma, serum, spot urine3

 

X

X

Whole saliva5

  

X

Clinical measures

Electrocardiogram

  

X

Heart rate

  

X

Brachial blood pressure

 

X

X

Central blood pressure

  

X

Aortic pulse wave velocity

  

X

Advanced glycation end-products

  

X

Anthropometric variables

Height

 

X

X

Weight

 

X

X

Waist circumference

 

X

X

Hip circumference

 

X

X

Body fat percentage

  

X

Abdominal fat distribution by ultrasound6

  

X

Hepatic fat content by ultrasound6

  

X

Physical activity

Combined accelerometer and heart rate monitor (ActiHeart)

  

X

Recent physical activity questionnaire (RPAQ)

  

X

Sleep questionnaire7

  

X

Questionnaire measures

Ethnicity / nationality

 

X

 

Education

 

X

 

Occupation

 

X

X

Personal medical history

 

X

X

Family history of diabetes

X

X

X

Family history of CVD

 

X

X

Current medication

  

X

Recent hospital admissions

  

X

Gestational diabetes (women only)

X

X

X

Lifestyle behaviours (smoking, alcohol consumption, physical activity)

 

X

X

Current weight, birth weight, weight loss/gain, perceived body image

  

X

EuroQol 5-D (health utility)

  

X

SF-36 (functional status)

  

X

Registry information

  

X

Cardiovascular disease

X

X

X

Type 2 diabetes

X

X

X

Medication use

X

X

X

Health service use

X

X

X

Mortality

  

X

  1. 1 Low diabetes risk <5 points on the diabetes risk score.
  2. 2 High diabetes risk ≥5 points on the diabetes risk score.
  3. 3 At screening, only for individuals with elevated RBG/FBG levels who progressed through to the later stages of the screening programme.
  4. 4 At ADDITION-PRO, only for individuals without incident diabetes since screening.
  5. 5 Only collected at the Steno Diabetes Center.
  6. 6 Only collected at the Steno Diabetes Center and in Aarhus.
  7. 7 Collected at the Steno Diabetes Center, Esbjerg and Aarhus from July 2010.