| South England | Midlands/ Wales | North England | Scotland | p-value^^ |
---|---|---|---|---|---|
Number of towns | 7 | 4 | 9 | 3 | Â |
Contacted | 2216 | 1199 | 2873 | 1008 | Â |
Responders at baseline (% of invited) | 1319 (60%) | 770 (64%) | 1650 (57%) | 547 (54%) | < 0.0005 |
Responders in 2003 (% baseline responders§) | 1141 (87%) | 633 (82%) | 1439 (87%) | 464 (85%) | 0.09 |
Responders in 2007 (% baseline responders§) | 846 (72%) | 450 (68%) | 1037 (71%) | 352 (74%) | 0.2 |
Classical and potential risk factors for CVD (baseline) | |||||
Age (mean (SD)) | 69.3 (5.5) | 69.5 (5.6) | 69.6 (5.5) | 68.9 (5.3) | 0.06 |
Smoking status | Â | Â | Â | Â | < 0.0005 |
   Never | 817 (62%) | 418 (54%) | 864 (52%) | 272 (50%) |  |
   Ex | 389 (30%) | 244 (32%) | 584 (36%) | 184 (34%) |  |
   Current | 108 (8%) | 101 (13%) | 195 (12%) | 91 (17%) |  |
   Missing | 5 (0.4%) | 7 (0.9%) | 7 (0.4%) | 0 (0%) |  |
Diabetes | Â | Â | Â | Â | 0.07 |
   Yes (SR/RR) | 67 (5.1%) | 49 (6.4%) | 86 (5.2%)^ | 31 (5.6%) |  |
   Yes (fasting glucose only) | 43 (3.3%) | 31 (4.0%) | 74 (4.5%) | 36 (6.6%) |  |
   No | 1209 (92%) | 690 (90%) | 1490 (90%) | 480 (88%) |  |
Systolic BP (sitting, mm/Hg)* | 153.2 (23.9) | 155.4 (23.9) | 154.6 (24.0) | 153.3 (25.4) | 0.20 |
   Missing | 114 (9%) | 150 (20%) | 141 (9%) | 16 (3%) |  |
LDL cholesterol (mmol/l) | 4.2 (1.1) | 4.2 (1.1) | 4.1 (1.1) | 4.1 (1.1) | 0.21 |
   Missing | 155 (12%) | 186 (24%) | 161 (10%) | 22 (4%) |  |
Waist circumference (mm)* | 861.0 (119.3) | 868.0 (120.7) | 861.9 (122.9) | 860.1 (125.8) | 0.63 |
   Missing | 84 (6%) | 126 (18%) | 123 (8%) | 3 (1%) |  |
Obesity | Â | Â | Â | Â | 0.29 |
   Yes | 430 (33%) | 341 (44%) | 565 (34%) | 163 (30%) |  |
   No | 813 (62%) | 296 (39%) | 967 (59%) | 382 (70%) |  |
   Missing | 76 (6%) | 133 (17%) | 118 (7%) | 2 (< 1%) |  |
Leg length (mm) | 763.5 (41.4) | 753.4 (42.9) | 756.1 (40.2) | 752.2 (39.5) | < 0.0005 |
   Missing | 75 (6%) | 133 (2%) | 118 (7%) | 2 (< 1%) |  |
Family history of CVD** | 750 (57%) | 431 (56%) | 893 (54%) | 300 (55%) | 0.49 |
Alcohol intake | Â | Â | Â | Â | < 0.0005 |
   Most days | 253 (19%) | 127 (17%) | 276 (17%) | 58 (11%) |  |
   Socially$ | 819 (62%) | 439 (57%) | 970 (59%) | 319 (58%) |  |
   Never | 166 (13%) | 133 (17%) | 239 (15%) | 109 (20%) |  |
   Missing | 81 (6%) | 71 (9%) | 165 (10%) | 61 (11%) |  |
Physically inactive$ | 739 (56%) | 510 (66%) | 935 (57%) | 285 (52%) | < 0.0005 |
   Missing | 149 (11%) | 90 (9%) | 214 (13%) | 97 (18%) |  |
Limited fruit/veg intake$$ | 33 (2%) | 44 (4%) | 93 (3%) | 40 (4%) | < 0.0005 |
   Missing | 129 (10%) | 83 (11%) | 242 (15%) | 90 (17%) |  |
Carstairs index based on GB population data (mean (SD)) | -0.9 (2.4) | 0.6 (2.7) | 0.5 (3.3) | 2.67 (3.4) | < 0.0005 |
   Missing | 24 (2%) | 1 (< 1%) | 8 (1%) | 36 (7%) |  |
Life-course SEP (median (25th, 75th centiles)) | 4 (2, 5) | 4 (3, 6) | 4 (2, 6) | 5 (3, 6) | < 0.0005 |
   Missing£ | 305 (23%) | 181 (24%) | 452 (27%) | 162 (30%) |  |
CVD medication | 487 (37%) | 252 (33%) | 673 (41%) | 262 (48%) | < 0.0005 |
Non-missing for all covariates | 700 (53%) | 382 (50%) | 881 (53%) | 293 (54%) | 0.3 |