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Table 3 Key selected indicators of progress in global implementation of measures for HIV and tuberculosis epidemic control

From: Re-thinking global health sector efforts for HIV and tuberculosis epidemic control: promoting integration of programme activities within a strengthened health system

Measure

HIV

Tuberculosis

diagnosis (proportion diagnosed among all with HIV or tuberculosis)

No global figure available in UNAIDS report [46]. Based on data from 12 low and middle-income countries, 20% of people with HIV infection know their status [46].

5.5 million cases diagnosed and treated in 2007 under programmes in line with global strategy to Stop TB/9.3 million estimated incident cases (59%) [13].

provision of first-line treatment (proportion receiving treatment among all those needing it)

ART 4 million/9.5 million at the end of 2007 [46] (42%)

 

treatment success rate

No global documentation of overall rate of successful treatment outcome ("highly heterogeneous monitoring systems and the use of non-standardised definitions across programmes create additional hurdles for accurately measuring the success of programmes") [46]

85% global treatment success rate in 2006 for patients with sputum smear-positive pulmonary tuberculosis treated in line with the global strategy to Stop TB [13].

 

Average retention in ART treatment programmes in sub-Saharan Africa was 75% after one year and 62% after two years [47].

75% treatment success rate (patients with sputum smear-positive pulmonary tuberculosis) in the WHO Africa region in 2006 [13].

drug-resistance surveillance

25 countries "were planning or implementing" WHO's global strategy for prevention and assessment of HIV drug resistance [48]. Seven countries have reported results [48].

Data from 90,726 patients in 83 countries and territories between 2002 and 2007 [49].

diagnosis of drug-resistant cases

No global figure available from UNAIDS report [46]. In nine countries reporting results from surveillance of transmitted HIV drug resistance from areas where ART was first used in the country, the prevalence of transmitted resistance was less than 5% [46].

30,000 cases of multidrug-resistance among people with smear-positive pulmonary tuberculosis diagnosed in 2007/353,000 estimated total worldwide (8.5%) [13].

provision of second-line treatment (proportion receiving treatment among all those needing it)

Results of a survey by national HIV programmes in 41 countries showed that 3% of people receiving ART were on second-line regimens [50]. The estimated number of people needing second-line ART is unknown.

3,681 cases of multidrug-resistance among people with smear-positive pulmonary tuberculosis known to be treated in 2007 according to international guidelines/353,000 estimated total worldwide cases (1%) [13].

treatment success rate (among people treated for drug-resistant HIV)

No global figure available from UNAIDS report [46].

Although "the size of most country cohorts in 2004 was too small to allow any useful analysis", treatment success rate ranged between about 50-70% for cohorts of patients treated according to international guidelines [13].