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Table 2 Concordance/discordance of mother-collected swabs vs. technician-collected paired swabs (n = 62 pairs) from households in Cincinnati, Ohio, and Boston, Massachusetts, USAa

From: Side-by-side comparison of parent vs. technician-collected respiratory swabs in low-income, multilingual, urban communities in the United States

Pathogenb

Detected in either Mother or Technician collected swabs

Concordant pairs

Discordant pairs

Kappa coefficient

(95% CI)

Mother negative and Technician negative

(−/−)

Mother positive and Technician positive (+/+)

Mother negative and Technician positive

(−/+)

Mother positive and Technician negative (+/−)

Any viruses

21

40

15

3

3

0.76**

(0.58–0.94)

Rhinovirus/Enterovirus

16

46

11

2

3

0.76**

(0.57–0.96)

Influenza A

1

61

1

0

0

1.0**

(1.0–1.0)

Influenza B

1

61

1

0

0

1.0**

(1.0–1.0)

Human Metapneumovirus

2

60

2

0

0

1.0**

(1.0–1.0)

Adenovirus

1

61

1

0

0

1.0**

(1.0–1.0)

Human Coronavirus OC43

2

60

1

1

0

0.66**

(0.04–1.0)

Parainfluenza 3

2

60

0

1

1

−0.02

(− 0.04–0.01)

Any bacteria

54

7

40

9

5

0.36

(0.08–0.62)

Haemophilus influenzae

25

37

12

6

7

0.50**

(0.26–0.73)

Streptococcus pneumoniae

27

34

14

7

7

0.50**

(0.27–0.72)

Chlamydia pneumoniae

2

60

2

0

0

1.0**

(1.0–1.0)

Group A Streptococcus

10

52

3

4

3

0.40*

(0.04–0.76)

Moraxella catarrhalis

14

48

9

1

4

0.73**

(0.52–0.95)

Staphylococcus aureus

39

22

25

9

5

0.52**

(0.30–0.73)

  1. Abbreviations: PPV positive predictive value, NPV negative predictive value
  2. * p < 0.01, ** p < 0.0001
  3. aPathogens included in the TaqMan array card used in the study. Cycle threshold (Ct) < 40 was interpreted as a positive result
  4. bThe following pathogens were not detected in any of the samples: Influenza C, Human Coronavirus (229, NL63, and HKU1), Parechovirus, Parainfluenza 1, 2, and 4, Respiratory Syncytial Virus, Legionella pneumophila, Bordetella pertussis, and Mycoplasma pneumoniae