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Table 2 Multinomial regressions predicting Langa-Weir classification of DEMENTIA and CIND at 18-year follow-up from baseline (1996) drinking group classification

From: History of drinking problems diminishes the protective effects of within-guideline drinking on 18-year risk of dementia and CIND

 

Unadjusted

Adjusted for demographic characteristics

Adjusted for demographic and health characteristics

 

OR

CI

W

p- value

OR

CI

W

p- value

OR

CI

W

p-value

DEMENTIA

 Baseline Characteristics

  Drinking Group

   ND: No HDP

_

_

_

_

_

_

_

_

_

_

_

_

   ND: Yes HDP

1.27

(0.89, 1.80)

1.74

.19

1.27

(0.86, 1.86)

1.44

.23

1.20

(0.81, 1.77)

0.81

.369

   WG: No HDP

0.33

(0.26, 0.43)

67.6

.00

0.52

(0.40, 0.69)

20.97

.00

0.55

(.041, .073)

17.34

.000

   WG: Yes HDP

0.63

(0.44, 0.91)

06.2

.01

0.91

(0.61, 1.35)

0.23

.63

0.87

(0.58, 1.30)

0.48

.490

   OG: No HDP

0.61

(0.30, 1.24)

1.88

.17

1.01

(0.48, 2.13)

0.00

.98

1.00

(0.47, 2.12)

0.00

.994

   OG: Yes HDP

0.50

(0.26, 0.98)

4.13

.04

0.77

(0.38, 1.56)

0.52

.47

0.73

(0.36, 1.47)

0.79

.375

  Demographic

   Age

    

1.14

(1.10, 1.19)

52.91

.00

1.15

(1.11, 1.19)

54.33

.000

   Female

    

0.95

(0.74, 1.20)

0.20

.66

0.89

(0.69, 1.14)

0.87

.351

   White

    

0.34

(0.26, 0.43)

74.74

.00

0.36

(0.28,0.46)

63.86

.000

   SES

    

0.28

(0.23, 0.33)

190.62

.00

0.30

(0.25, 0.36)

155.23

.000

  Health

   N medical conditions

        

1.24

(1.11, 1.38)

15.19

.000

   Smoking

        

1.50

(1.11, 2.02)

7.14

.008

   BMI

        

1.02

(1.00, 1.04)

2.75

.097

   Depression

        

1.07

(0.99, 1.14)

3.32

.069

CIND

 Baseline Characteristics

  Drinking Group

   ND: No HDP

_

_

_

_

_

_

_

_

_

_

_

_

   ND: Yes HDP

1.41

(1.08, 1.85)

06.4

.01

1.33

(0.99, 1.78)

3.69

.055

1.26

(0.94, 1.69)

2.40

.121

   WG: No HDP

0.57

(0.48, 0.67)

42.3

.00

0.78

(0.65, 0.94)

6.87

.009

0.79

(.065, .095)

6.28

.012

   WG: Yes HDP

0.78

(0.60, 1.00)

03.6

.06

0.98

(0.74, 1.30)

0.02

.891

0.95

(0.71, 1.26)

0.14

.706

   OG: No HDP

0.68

(0.40, 1.13)

2.23

.14

0.97

(0.56, 1.67)

0.01

.914

0.89

(0.51, 1.57)

0.15

.695

   OG: Yes HDP

0.92

(0.61, 1.37)

0.17

.68

1.21

(0.79, 1.86)

0.75

.385

1.08

(0.70, 1.68)

0.13

.719

  Demographic

   Age

    

1.08

(1.05, 1.10)

31.30

.000

1.08

(1.05, 1.11)

35.0

.000

   Female

    

0.83

(0.70, 0.98)

5.06

.024

0.79

(0.66, 0.93)

7.79

.005

   White

    

0.36

(0.30, 0.44)

113.31

.000

0.39

(0.32, 0.47)

96.83

.000

   SES

    

0.41

(0.36, 0.47)

195.95

.000

0.44

(0.39, 0.50)

159.36

.000

  Health

   N medical conditions

        

1.16

(1.07, 1.26)

13.70

.000

   Smoking

        

1.41

(1.14, 1.75)

10.24

.001

   BMI

        

1.01

(1.00, 1.03)

02.55

.111

   Depression

        

1.09

(1.03, 1.14)

10.17

.001

-Log-Likelihood

68.96 (X2 = 133.86, df = 10, p = .000)

464.02 (X2 = 811.73, df = 18, p = .000)

6118.11 (X2 = 861.09, df = 26, p = .001)

Nagelkerke Pseudo R2 = .

.037

.210

.225

  1. Note: ND Non-Drinker, WG Within-Guideline, OG Outside-Guideline, OR Odds ratio, CI Confidence interval, W Wald statistic