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Table 1 Hypothetical health state scenarios relating to oral HPV infection and oropharyngeal cancer, ranks and percentages of perfect health by six health states lasting 12 months, standard gamble utility scores and intra-class correlation coefficient for OPSCC duration among Indigenous adults (n = 1011)

From: Population-based utility scores for HPV infection and oropharyngeal squamous cell carcinoma among Indigenous Australians

Codes

Health states

Description

Rank

Perfect health lasting 12 months (%)

Oropharyngeal cancer duration

12 months

Lifetime

 

Median (IQR)

Mean (SD)

Median (IQR)

Mean (SD)

Median (IQR)

Mean (SD)

Median (IQR)

ICC

S1

Screened; cytology normal

OPSCC screening test cytology negative (Roger)

1 (1)

85.1 (16.7)

90.0 (20.0)

0.91 (0.28)

1.00 (0.04)

0.91 (0.28)

1.00 (0.10)

0.99959

S2

HPV vaccination

Three doses of HPV vaccine (Emily)

2 (2)

79.8 (19.2)

85.0 (23.5)

0.92 (0.27)

1.00 (0.01)

0.91 (0.28)

1.00 (0.01)

0.99793

S3

Screened; HPV positive, endoscopy normal

HPV positive and cytology negative; follow-up OPSCC screening in 12 months (Sam)

3 (1)

69.0 (18.2)

70.0 (20.0)

0.92 (0.28)

1.00 (0.01)

0.91 (0.28)

1.00 (0.01)

0.99309

S4

Oral warts

Treatment for oral warts associated with HPV infection (Rachel)

4 (1)

68.0 (20.5)

70.0 (26.5)

0.88 (0.32)

1.00 (0.00)

0.88 (0.32)

1.00 (0.00)

0.99998

S5

HG cytology with OIN II-III

High grade cytology with histologically-confirmed grade II/III oral intraepithelial neoplasia (Max)

5 (0)

48.6 (20.4)

50.0 (20.0)

0.87 (0.34)

1.00 (0.14)

0.87 (0.34)

1.00 (0.11)

0.99664

S6

Early stage invasive throat cancer

Early stage invasive throat cancer requiring laryngectomy (Mary)

6 (0)

25.9 (21.5)

20.0 (30.0)

0.75 (0.43)

1.00 (0.81)

0.79 (0.40)

1.00 (0.00)

0.45521

  1. Interquartile range (IQR) being the difference between 75th (Q3) and 25th (Q1) percentiles (IQR = Q3-Q1)
  2. HPV human papillomavirus, OPSCC oropharyngeal squamous cell carcinoma, HG high grade, OIN oral intraepithelial neoplasia