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Table 3 Hazard ratio (95% confidence intervals) of developing diabetes based on quartiles of inflammatory indices

From: Dietary and lifestyle inflammatory scores and risk of incident diabetes: a prospective cohort among participants of Tehran lipid and glucose study

 

Quartiles of scores

P for trend

 

Q1

Q2

Q3

Q4

 

EDIP

 Median score

0.19

0.39

0.57

0.91

 

 Case/Total

71 / 1156

90 / 1154

74 / 1156

94 / 1155

 

 Follow-up time

5.76 (1.51)

5.69 (1.55)

5.74 (1.57)

5.66 (1.640

 

 Model 1*

1.00 (Ref)

1.36 (0.99–1.88)

1.16 (0.83–1.63)

1.60 (1.17–2.19)

0.009

 Model 2†

1.00 (Ref)

1.36 (0.99–1.88)

1.11 (0.79–1.58)

1.55 (1.11–2.17)

0.026

 Model 3‡

1.00 (Ref)

1.40 (1.01–1.93)

1.32 (0.86–1.72)

1.52 (1.08–2.14)

0.038

DIS

 Follow-up time

5.71 (1.58)

5.71 (1.57)

5.69 (1.58)

5.74 (1.55)

 

 Median score

−1.01

−0.21

0.32

1.01

 

 Case/Total

100 / 1155

87 / 1155

80 / 1155

62 / 1155

 

 Model 1*

1.00 (Ref)

0.96 (0.72–1.30)

0.95 (0.70–1.28)

0.83 (0.59–1.15)

0.286

 Model 2†

1.00 (Ref)

1.06 (0.79–1.44)

1.02 (0.75–1.40)

0.91 (0.65–1.28)

0.640

 Model 3‡

1.00 (Ref)

0.85 (0.72–1.31)

0.89 (0.71–1.34)

0.36 (0.61–1.20)

0.418

LIS

 Follow-up time

5.80 (1.48)

5.80 (1.51)

5.73 (1.54)

5.51 (1.72)

 

 Median score

−0.18

0.48

0.89

1.39

 

 Case/Total

34 / 1297

84 / 1401

53 / 721

157 / 1201

 

 Model 1*

1.00 (Ref)

1.99 (1.31–3.01)

2.29 (1.46–3.59)

4.26 (2.88–6.30)

<  0.001

 Model 2¶

1.00 (Ref)

1.97 (1.30–2.99)

2.26 (1.44–3.56)

4.18 (2.83–6.20)

<  0.001

 Model 3§

1.00 (Ref)

1.53 (1.01–2.34)

1.38 (0.87–2.21)

2.41 (1.61–3.60)

<  0.001

  1. *Model 1: adjusted for age and sex.
  2. †Model 2: adjusted for model 1 and energy, body mass index, smoking, physical activity, education level
  3. ‡Model 3: adjusted for model 2 and hypertension, fasting blood sugar, and TG to HDL ratio
  4. ¶Model2: adjusted for model 1 and energy and education level
  5. §Model 3: adjusted for model 1 and energy, education level, hypertension, fasting blood sugar, and TG to HDL ratio