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Table 2 Distribution (%) of socio-demographic, lifestyle, and health characteristics in men and women by absence of diastolic left ventricular dysfunction (DLVD), presence of DLVD without symptoms (ADLVD), and presence of DLVD with symptoms (SDLVD)

From: Sex differences in factors associated with heart failure and diastolic left ventricular dysfunction: a cross-sectional population-based study

Characteristic

Men

Women

Without DLVD

N = 449

ADLVD

N = 315

SDLVD

N = 93

Without DLVD

N = 437

ADLVD

N = 301

SDLVD

N = 81

Age (m, sd) †‡

 

72 (4)

74 (5)

76 (5)

72 (5)

74 (5)

75 (5)

Education level

<= Primary School

26.3*

25.4*

33.5

36.8*

41.9*

44.5

Junior High School

24*

20.6*

17.2

23.3*

21.6*

22.2

> = High School

49.7*

54.0*

47.3

39.8*

36.5*

33.3

Smoking habit †

Never

32.3*

31.8*

17.2*

66.1*

67.1*

66.7*

Ever

67.7*

68.2*

82.8*

33.9*

32.9*

33.3*

Alcohol consumption

No

26.5*

26.0*

31.2*

56.5*

55.5*

56.8*

Yes

73.5*

74.0*

68.8*

43.5*

44.5*

43.2*

Physical activity

No

49.9*

54.6

61.3

60.9*

62.1

74.1

Occasionally

25.6*

21.0

21.5

21.1*

20.3

13.6

Daily

24.5*

24.4

17.2

18.0*

17.6

12.3

BMI ‡

> = 30

13.6*

15.9*

17.2

15.3*

18.6*

27.2

25–29.9

51.0*

50.5*

54.8

33.4*

33.9*

50.6

< 25

35.4*

33.6*

28.0

51.3*

47.5*

22.2

Dyslipidemia

No

61.5*

64.1*

69.9*

45.5*

50.8*

48.2*

Yes

38.5*

35.9*

30.1*

54.5*

49.2*

51.8*

Diabetes †

No

85.1

75.9*

77.4

89.0

83.4*

84.0

Yes

14.9

24.1*

22.6

11.0

16.6*

16.0

Hypertension †‡

No

45.9

39.0

30.1

44.4

39.9

24.7

Yes

54.1

61.0

69.9

55.6

60.1

75.3

Family history of CVD

No

81.5*

85.1*

78.5

76.0*

75.7*

66.7

Yes

18.5*

14.9*

21.5

24.0*

24.3*

33.3

Ischemic heart diseasea †

No

86.6*

83.8*

59.1*

92.9*

93.0*

87.7*

Yes

13.4*

16.2*

40.9*

7.1*

7.0*

12.3*

Atrial fibrillation †

No

94.0

93.0

81.7

93.8

94.0

88.9

Yes

6.0

7.0

18.3

6.2

6.0

11.1

Other cardiovascular diseaseb

No

94.7

94.6

89.3

94.3

94.0

91.4

Yes

5.3

5.4

10.7

5.7

6.0

8.6

Other conditionsc †

No

52.6*

55.2

41.9*

42.3*

46.2

34.6*

1–2

42.3*

38.1

40.9*

45.8*

44.5

60.5*

3+

5.1*

6.7

17.2*

11.9*

9.3

4.9*

Use of diuretics †‡

No

81.3

76.5

64.5

76.9

73.8

50.6

Yes

18.7

23.5

35.5

23.1

26.3

49.4

Use of ARBs ‡

No

78.2

75.9

75.3

78.0

74.8

61.7

Yes

21.8

24.1

24.7

22.0

25.3

38.3

Use of Angiotensin-converting enzyme inhibitors †

No

74.8*

70.8

55.9

80.6*

77.1

75.3

Yes

25.2

29.2

44.1

19.5

22.9

24.7

Mineralocorticoid receptor antagonists

No

98.4

98.7

94.6

99.1

99.3

96.3

Yes

1.6

1.3

5.4

0.9

0.7

3.7

Beta blockers †‡

No

85.1

81.9

68.8

83.3

83.7

71.6

Yes

14.9

18.1

31.2

16.7

16.3

28.4

Statins

No

77.5

78.4

67.7

72.1

76.1

72.8

Yes

22.5

21.6

32.3

27.9

23.9

27.2

Antiarrhythmic drugs †

No

96.9

96.8

89.3

96.1

96.7

95.1

Yes

3.1

3.2

10.8

3.9

3.3

4.9

Antiaggregant drugs †

No

72.2

67.3

57.0

76.4

74.4

67.9

Yes

27.8

32.7

43.0

23.6

25.6

32.1

Calcium channel blockers

No

81.1

77.8*

74.2

84.9

84.1*

75.3

Yes

18.9

22.2*

25.8

15.1

16.0*

24.7

Creatinine level (mg/dl)

(mean, sd) †‡

1.04 (0.23)*

1.08 (0.29)*

1.14 (0.33)*

0.84 (0.24)*

0.86 (0.21)*

0.91 (0.26)*

% Ejection Fraction (mean,sd) †‡

67.1 (5.8)*

64.1 (8.1)*

56.9 (12.1)*

68.2 (5.5)*

67.1 (6.2)*

64.0 (8.7)*

E/A ratio (mean,sd) †‡

0.85 (0.18)

0.74 (0.25)

0.86 (0.25)

0.86 (0.18)

0.72 (0.21)

0.76 (0.37)

E/e’ (mean,sd) †‡

6.7 (2.2)*

8.8 (2.8)*

9.3 (3.2)*

7.4 (2.4)*

9.6 (3.3)*

11 (5.6)*

NT-pro BNP (pg/mL) (median, P25-P75) †‡

63 (33–125)*

88 (42–182)

291 (92–756)*

99 (51–177)*

96 (53–167)

132 (78–276)*

  1. aEither angina pectoris, or myocardial infarction, or revascularization procedures
  2. bEither peripheral vascular disease or valve disease
  3. cNumber of other conditions among stroke, TIA, COPD, liver disease, thyroid disorders, blood disease, gastric disorders, renal disease, Parkinson’s disease, other disease of CNS, and cancer
  4. *The difference between men and women in the total population or between men and women in each condition is statistically significant p < 0.05
  5. †The differences across groups of DLVD are statistically significant in men (p < 0.05)
  6. ‡The differences across groups of DLVD are statistically significant in women (p < 0.05)