Associations of total and type-specific physical activity with mortality in chronic obstructive pulmonary disease: a population-based cohort study

Cheng, Sonia Wing Mei; McKeough, Zoe; Alison, Jennifer; Dennis, Sarah; Hamer, Mark; Stamatakis, Emmanuel

doi:10.1186/s12889-018-5167-5

Table 3 The associations of type-specific physical activity with mortality risk in participants with COPD (n = 2155)

From: Associations of total and type-specific physical activity with mortality in chronic obstructive pulmonary disease: a population-based cohort study

	Walking				Domestic PA				Sport/exercise
	Cases/No.	Model 1 HR (95% CI)	Model 2 HR (95% CI)	Model 3 HR (95% CI)	Cases/No.	Model 1 HR (95% CI)	Model 2 HR (95% CI)	Model 3 HR (95% CI)	Cases/No.	Model 1 HR (95% CI)	Model 2 HR (95% CI)	Model 3 HR (95% CI)
All-cause mortality (571 deaths)
No PA^a	245/733	1.00	1.00	1.00	320/1040	1.00	1.00	1.00	473/1556	1.00	1.00	1.00
Low PA^b	186/708	0.71 (0.58–0.85)	0.79 (0.65–0.96)	0.88 (0.72–1.08)	133/529	0.70 (0.57–0.86)	0.77 (0.62–0.94)	0.86 (0.70–1.06)	49/288	0.64 (0.48–0.87)	0.68 (0.51–0.92)	0.77 (0.57–1.05)
High PA^c	140/714	0.52 (0.42–0.64)	0.61 (0.49–0.76)	0.70 (0.56–0.88)	118/586	0.67 (0.54–0.82)	0.75 (0.60–0.93)	0.85 (0.68–1.07)	49/311	0.53 (0.39–0.71)	0.59 (0.44–0.80)	0.69 (0.51–0.93)
P trend		< 0.001	< 0.001	0.002		0.001	0.027	0.234		< 0.001	0.004	0.037
CVD mortality (172 deaths)
No PA	86/733	1.00	1.00	1.00	106/1040	1.00	1.00	1.00	152/1556	1.00	1.00	1.00
Low PA	51/708	0.56 (0.39–0.79)	0.66 (0.47–0.94)	0.72 (0.50–1.03)	31/529	0.50 (0.34–0.75)	0.61 (0.40–0.92)	0.70 (0.46–1.06)	10/288	0.42 (0.22–0.80)	0.43 (0.23–0.82)	0.50 (0.26–0.96)
High PA	35/714	0.38 (0.25–0.56)	0.49 (0.33–0.74)	0.56 (0.36–0.85)	35/586	0.62 (0.42–0.91)	0.78 (0.52–1.16)	0.94 (0.62–1.42)	10/311	0.34 (0.18–0.64)	0.43 (0.23–0.83)	0.50 (0.26–0.96)
P trend		< 0.001	0.002	0.012		0.071	0.431	0.972		0.006	0.046	0.096
Respiratory mortality (105 deaths)
No PA	50/733	1.00	1.00	1.00	60/1040	1.00	1.00	1.00	93/1556	1.00	1.00	1.00
Low PA	37/708	0.67 (0.44–1.03)	0.77 (0.50–1.18)	0.92 (0.58–1.47)	30/529	0.79 (0.51–1.23)	0.80 (0.51–1.26)	1.13 (0.70–1.84)	4/288	0.27 (0.10–0.74)	0.34 (0.12–0.92)	0.44 (0.16–1.20)
High PA	18/714	0.32 (0.18–0.54)	0.38 (0.22–0.67)	0.47 (0.26–0.85)	15/586	0.43 (0.25–0.76)	0.49 (0.27–0.87)	0.63 (0.34–1.15)	8/311	0.44 (0.21–0.90)	0.49 (0.24–1.03)	0.73 (0.34–1.54)
P trend		< 0.001	0.001	0.009		0.005	0.018	0.098		0.134	0.203	0.690

PA physical activity, HR hazard ratio, CVD cardiovascular disease
Model 1: adjusted for age and sex; Model 2: also adjusted for COPD severity, history of cardiovascular disease, history of cancer, history of diabetes, self-reported longstanding illness and body mass index; Model 3: also adjusted for smoking status, education level, alcohol consumption and the two other type-specific PA variables
^a“No PA” was defined as no self-reported walking during the week, no self-reported domestic physical activity during the week, and no self-reported sport/exercise during the week
^b“Low PA” was defined as < 5.25 MET-hours/week of walking, < 5.70 MET-hours/week of domestic physical activity, and < 8.00 MET-hours/week of sport/exercise
^c“High PA” was defined as ≥5.25 MET-hours/week of walking, ≥5.70 MET-hours/week of domestic physical activity, and ≥8.00 MET-hours/week of sport/exercise

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