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Table 4 Odds of having individual metabolic syndrome components according to use of antidepressant medications in the Maine-Syracuse Longitudinal Study

From: Association between depressive symptoms, use of antidepressant medication and the metabolic syndrome: the Maine-Syracuse Study

Predictor

Covariate seta

Group

MetS elevated glucoseb

MetS hypertensionb

MetS low HDL-cholesterolb

   

OR

95 % CI

P

OR

95 % CI

P

OR

95 % CI

P

Antidepressant medication use

Basic

Yes

2.01

1.30, 3.13

0.002

1.99

1.21, 3.25

0.006

1.66

1.10, 2.51

0.015

 

No

1.00

  

1.00

  

1.00

  
 

Extended

Yes

1.95

1.23, 3.09

0.005

1.81

1.09, 3.02

0.023

1.57

1.03, 2.40

0.036

  

No

1.00

  

1.00

  

1.00

  
  1. CI, confidence interval; MetS, metabolic syndrome; OR, odds ratio
  2. aBasic: adjusted for age, education, sex, ethnicity; Extended: adjusted for set 1 + smoking (cigarettes per day), physical activity (MET-minutes/day), CRP (mg/L)
  3. bMetS clinical cut off points: elevated fasting plasma glucose: ≥5.6 mmol/L or ≥100 mg/dL; elevated blood pressure: systolic: ≥130 and/or diastolic ≥85 mmHg; reduced HDL-cholesterol: <1.0 mmol/L or <40 mg/dL for males; <1.3 mmol/L or <50 mg/dL for females [1]