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Table 3 Univariate and multivariate Cox proportional hazard models: the association of treatment careers and co-factors with mortality in the DC WIHS (n = 329)

From: Trajectory analyses of virologic outcomes reflecting community-based HIV treatment in Washington DC 1994–2012

Variables

Univariate analysis

P value

Multivariate analysis

P value

HR

(95 % CI)

HR

(95 % CI)

Race

  

0 · 09

  

0 · 94

 White

Referent

     

 Black

2 · 49

(1 · 08,5 · 76)

0 · 03

1 · 2

(0 · 47,3 · 07)

0 · 71

 Hispanic

1 · 02

(0 · 26,4 · 09)

0 · 98

0 · 81

(0 · 15,4 · 31)

0 · 8

 Other

1 · 88

(0 · 38,9 · 35)

0 · 44

1 · 25

(0 · 14,11 · 13)

0 · 84

Education

      

  < 12 years

Referent

    

  > = 12 years

0 · 75

(0 · 46,1 · 24)

0 · 26

   

Age

1 · 05

(1 · 03,1 · 08)

0 · 0003

1 · 06

(1 · 02,1 · 09)

0 · 004

Housinga

      

 No housing

Referent

    

 Housing

0 · 86

(0 · 48,1 · 53)

0 · 6

   

Depressiona

      

 Depression score <16

Referent

    

Depression score > =16

1 · 71

(1 · 02,2 · 86)

0 · 04

0 · 94

(0 · 54,1 · 64)

0 · 83

Drug Abusea

      

 No reported drug use

Referent

    

 Reported drug use

2 · 01

(1 · 2,3 · 37)

0 · 008

1 · 57

(0 · 91,2 · 7)

0 · 11

CD4a

0 · 65

(0 · 56,0 · 75)

<0 · 0001

0 · 69

(0 · 6,0 · 8)

<·0001

ARTa

      

 No ART use

Referent

     

 ART use

1 · 69

(0 · 97,2 · 93)

0 · 06

1 · 09

(0 · 58,2 · 04)

0 · 8

cARTa

      

 No cART use

Referent

     

 cART use

1 · 06

(0 · 62,1 · 8)

0 · 84

   

Adherencea

      

 < 95 % therapy use

Referent

     

 > = 95 % therapy use

0 · 64

(0 · 32,1 · 27)

0 · 2

   

HIV treatment career

  

<0 · 0001

  

<·0001

 Nonviremia

Referent

     

 Intermittent

0 · 83

(0 · 31,2 · 24)

0 · 71

0 · 59

(0 · 18,1 · 94)

0 · 38

 Viremia

5 · 25

(2 · 4,11 · 47)

<0 · 0001

3 · 967

(1 · 53,10 · 28)

0 · 0045

Alcohol use > = 7 drinks/week since last visita

1 · 432

(0 · 704,2 · 912)

0 · 322

   
  1. Multivariate model included race, age, depression, drug abuse, CD4, ART and HIV treatment career
  2. Abbreviations: CI 95 % confident interval, CES-D Center for Epidemiologic studies of depression scale, cART highly active antiretroviral therapy, HR Hazard ratio
  3. a: time-dependent variables