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Table 1 The CHD mortality fall in Ireland attributable to risk factor changes in individuals with and without recognised coronary heart disease, including sensitivity analyses (minimum and maximum estimates)

From: Comparing primary prevention with secondary prevention to explain decreasing Coronary Heart Disease death rates in Ireland, 1985–2000

  Relative change in population risk factor level (%) Deaths prevented or postponed * (minimum and maximum estimates)   
   In healthy subjects (Primary prevention) In CHD patients (Secondary Prevention) TOTALS
SMOKING Total Change -14.2% 275 (20–485) 410 (310–800) 685 (330 – 1,285)
CHOLESTEROL Total change -4.6% 1,230 (1060–1,520) 375 (170–770) 1,605 (1,230 – 2,290)
Fall Attributable to diet   1,185 (1050–1,445) 115(65–215) 1,300 (1,115–1,660)
Fall Attributable to statins   45(10–75) 260 (105–555) 305 (115–630)
BLOOD PRESSURE Total Change -7.2% 210 (115–365) 30 (20–65) 240 (135–430)
Secular trends   140(85–235) 30(20–65) 170 (105–300)
Hypertension therapy   70(30–130) ** 70(30–130)
All 3 major risk factors   1,715(68%) (1,195–2,370) 815(32%) (500–1,635) 2,530 (1,695–4,005)
  1. *All numbers were rounded to the nearest 5;
  2. **Hypertension therapy in CHD patients already quantified within the secondary prevention medication component of the IMPACT Model.