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Table 7 Adjusted odds ratios for various factors that might affect treatment outcomes among registered tuberculosis patients

From: DOTS improves treatment outcomes and service coverage for tuberculosis in South Ethiopia: a retrospective trend analysis

 

Treatment success (all TB)

Default (all TB)

Characteristic

Percent1

Adjusted OR* (95% CI)

p-value

Percent1

Adjusted OR* (95% CI)

p-value

Sex

      

Male

45.5

1.00

 

37.5

1.00

 

Female

49.4

1.15(1.08–1.23)

<0.001

34.0

0.88(0.82–0.94)

<0.001

Age group (years)

      

0–14

42.6

0.83 (0.75–0.92)

<0.001

41.2

1.17 (1.06–1.30)

0.002

15–24 (reference group)

51.1

1.00

 

33.4

1.00

 

25–34

47.5

0.84(0.77–0.91)

<0.001

34.4

1.07 (0.98–1.17)

0.14

35–44

45.7

0.76 (0.68–0.84)

<0.001

36.1

1.14 (1.03–1.28)

0.02

45–54

44.9

0.69 (0.60–0.79)

<0.001

37.7

1.26 (1.09–1.46)

0.002

55–64

51.4

1.04 (0.84–1.29)

0.71

35.4

1.04 (0.81–1.27)

0.90

≥ 65

37.4

0.67 (0.48–0.93)

0.02

43.7

1.27 (0.92–1.726

0.15

Patient category

      

New

47.0

1.00

 

35.9

1.00

 

Transferred-in

59.5

1.09 (0.89–1.36)

0.40

35.7

1.19 (0.95–1.48)

0.13

Return after default

33.9

0.68 (0.51–0.92)

0.01

52.9

1.57 (1.19–2.07)

0.002

Treatment failure

54.3

1.30 (0.91–1.86)

0.15

23.6

0.72 (0.48–1.09)

0.12

Relapse

62.9

1.51(1.01–2.26)

0.05

16.9

0.50 (0.30–0.82)

0.006

TB type

      

Pulmonary positive

55.3

1.00

 

28.7

1.00

 

Pulmonary negative

37.5

0.55 (0.50–0.60)

<0.001

43.7

2.06 (1.87–2.26)

<0.001

Extra-pulmonary

42.4

0.51 (0.47–0.55)

<0.001

41.1

1.94 (1.78–2.11)

<0.001

Treatment regimen

      

Short course chemotherapy

55.5

1.00

 

27.7

1.00

 

Long course chemotherapy

45.0

0.68 (0.62–0.75)

<0.001

40.9

1.46 (1.33–1.61)

<0.001

Treatment Centre**

      

Hossana Hospital

27.0

1.00

 

40.0

1.00

 

Lemmo district HF

60.4

5.14 (4.62–5.72)

<0.001

20.6

0.28 (0.25–0.31)

<0.001

Shashogo district HF

50.8

2.81 (2.41–3.28)

<0.001

44.1

1.18 (1.01–1.37)

0.04

Misha district HF

60.3

4.78 (4.23–5.39)

<0.001

33.0

0.58 (0.51–0.65)

<0.001

Gibe district HF

60.7

4.78 (4.20–5.45)

<0.001

26.2

0.51 (0.45–0.59)

<0.001

Soro district HF

50.5

2.70 (2.39–3.06)

<0.001

42.5

1.11 (0.98–1.26)

0.09

Duna district HF

30.2

0.77 (0.55–1.08)

0.12

67.3

5.18 (3.71–7.24)

<0.001

Badewacho district HF

41.1

1.64 (1.44–1.86)

<0.001

54.4

2.11 (1.86–2.40)

<0.001

Year of treatment

      

1994

38.4

1.00

 

42.7

1.00

 

1995

40.6

1.18 (0.99–1.39)

0.06

39.9

1.17 (1.00–1.37)

0.05

1996

48.7

1.29 (1.10–1.51)

0.002

33.3

0.83 (0.71–0.97)

0.02

1997

38.9

0.72 (0.61–0.85)

<0.001

39.5

1.08 (0.93–1.27)

0.32

1998

41.9

0.74 (0.63–0.87)

<0.001

43.8

1.20 (1.03–1.40)

0.02

1999

56.7

1.37 (1.16–1.62)

<0.001

30.0

0.59 (0.5–0.70)

<0.001

2000

59.8

1.41 (1.18–1.69)

<0.001

25.8

0.54 (0.45–0.65)

<0.001

  1. OR = odds ratio; CI = confidence intervals; HF = Health facilities
  2. * All the variables in the table are included in the model.
  3. ** All treatment centres in a district grouped together as a unit.
  4. 1 Percentage out of total registered for treatment. Patients with missing outcome record were assumed to have defaulted and analysed as defaulters.