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Table 4 Factors associated with poor ART adherence during pregnancy

From: Adherence to antiretroviral therapy during pregnancy and the first year postpartum among HIV-positive women in Ukraine

 

CASE score ≤11 points (25/173)

Fisher’s exact test

≥1 missed dose (61/176)

Fisher’s exact test

Age

    

<25 years

26% (11/42)

p = 0.13

52% (23/44)

p = 0.03

25-27 years

10% (5/48)

 

23% (11/48)

 

28-30 years

12% (5/41)

 

29% (12/41)

 

≥31 years

10% (4/42)

 

35% (15/43)

 

Marital status

    

Married

14% (13/93)

p = 0.96

34% (32/95)

p = 0.83

Cohabiting

15% (7/48)

 

33% (16/48)

 

Single

16% (5/32)

 

39% (13/33)

 

Pregnancy planned

    

Yes

11% (13/120)

p = 0.03

30% (36/122)

p = 0.02

No

25% (12/48)

 

49% (24/49)

 

Lives with family

    

No

10% (12/115)

p = 0.04

29% (34/117)

p = 0.04

Yes

23% (13/57)

 

46% (26/57)

 

Lives with partner

    

No

18% (9/49)

p = 0.47

45% (22/49)

p = 0.08

Yes

13% (16/123)

 

30% (38/125)

 

Disclosed HIV status to anyone

    

No

20% (3/15)

p = 0.46

38% (6/16)

p = 0.79

Yes

14% (22/157)

 

35% (55/159)

 

Current smoker

    

No

14% (18/127)

p = 1.00

30% (39/129)

p = 0.07

Yes

14% (6/44)

 

47% (21/45)

 

History of drug use (other than marijuana)

    

No

14% (21/146)

p = 1.00

35% (52/149)

p = 1.00

Yes

14% (3/21)

 

33% (7/21)

 

Self-efficacy score

    

≥5 (higher self-efficacy)

12% (13/107)

p = 0.22

28% (30/108)

p = 0.04

<5 (lower self-efficacy)

22% (6/27)

 

50% (14/28)

 

Positive depression screen

    

No

13% (16/124)

p = 0.33

31% (39/125)

p = 0.08

Yes

20% (9/46)

 

46% (22/48)

 

Can you ask doctor for support?

    

Certain/fairly certain

14% (21/155)

p = 0.06

33% (52/156)

p = 0.34

Cannot do

36% (4/11)

 

50% (6/12)

 

Antenatal ART

    

Zidovudine monotherapy

29% (4/14)

p = 0.23

64% (9/14)

p = 0.02

cART

13% (19/141)

 

31% (44/143)

 

Severity of ART side effects

    

Not bothered or only slightly

14% (18/126)

p = 0.81

33% (42/127)

p = 0.71

Somewhat or terribly bothered

16% (7/43)

 

37% (16/43)

 

Knowledge of whether antenatal ART is effective for PMTCT

    

Completely or fairly sure that it is effective

12% (20/162)

p = 0.10

33% (54/165)

p = 0.17

Unsure that it is effective

33% (3/9)

 

56% (5/9)

 
  1. p values ≤0.5 are indicated in bold.