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Table 4 Prevalence, number of edges, degree and betweenness centrality of diseases by gender and multimorbidity clusters in the population with ≥ 3 chronic conditions

From: Reducing complexity: a visualisation of multimorbidity by combining disease clusters and triads

ADS and pain

Prevalence in patients

Number of edges (degree centrality)

Betweenness centrality

Total

Females

Males

Females

Males

Females

Males

Chronic low back pain

43.7%

47.1%

41.0%

16 (8.0%)

16 (9.2%)

28.4%

32.2%

Joint arthrosis

28.7%

33.6%

24.8%

10 (5.0%)

9 (5.2%)

4.9%

5.7%

Lower limb varicosis

16.4%

22.7%

11.5%

7 (3.5%)

2 (1.1%)

3.1%

0.0%

Prostatic hyperplasia

*

-

28.1%

-

5 (2.9%)

-

2.6%

Asthma/COPD

15.3%

14.1%

16.3%

3 (1.5%)

4 (2.3%)

0.4%

0.1%

Depression

12.4%

18.1%

7.8%

10 (5.0%)

2 (1.1%)

11.9%

0.0%

Chronic gastritis/GERD

10.8%

10.8%

10.8%

7 (3.5%)

3 (1.7%)

2.7%

0.1%

Osteoporosis

10.7%

19.7%

3.6%

2 (1.0%)

-

0.0%

-

Gynaecological problems

*

16.6%

-

3 (1.5%)

-

0.1%

-

Allergies

7.3%

8.5%

6.3%

3 (1.5%)

-

0.4%

-

Insomnia

6.6%

7.6%

5.8%

4 (2.0%)

2 (1.1%)

0.2%

0.0%

Intestinal diverticulosis

6.3%

6.4%

6.2%

2 (1.0%)

2 (1.1%)

0.0%

0.0%

Hemorrhoids

6.1%

5.2%

6.8%

2 (1.0%)

4 (2.3%)

0.0%

0.4%

Somatoform disorders

5.9%

7.7%

4.5%

5 (2.5%)

-

1.1%

-

Severe hearing loss

4.6%

3.8%

5.2%

-

2 (1.1%)

-

0.0%

Dizziness

4.2%

5.4%

3.4%

2 (1.0%)

-

0.0%

-

Anxiety

2.5%

3.7%

1.6%

2 (1.0%)

-

0.0%

-

Sexual dysfunction

*

-

4.5%

-

2 (1.1%)

-

0.0%

Cardiovascular and metabolic

       

Hypertension

69.3%

69.3%

69.4%

13 (6.5%)

9 (5.2%)

12.0%

12.0%

Lipid metabolism disorders

47.4%

46.7%

48.0%

11 (5.5%)

8 (4.6%)

5.8%

1.4%

Diabetes mellitus

28.5%

24.9%

31.4%

14 (7.0%)

11 (6.3%)

5.8%

5.0%

Chronic ischemic heart disease

25.7%

18.2%

31.6%

13 (6.5%)

10 (5.7%)

5.1%

2.8%

Hyperuricemia/Gout

18.1%

11.3%

23.5%

11 (5.5%)

12 (6.9%)

5.2%

7.8%

Cardiac arrhythmias

18.0%

15.5%

20.0%

6 (3.0%)

8 (4.6%)

0.2%

4.3%

Atherosclerosis/PAOD

13.7%

10.3%

16.4%

8 (4.0%)

10 (5.7%)

2.6%

5.7%

Obesity

12.4%

13.4%

11.7%

9 (4.5%)

7 (4.0%)

2.2%

3.8%

Liver diseases

12.0%

9.9%

13.7%

7 (3.5%)

8 (4.6%)

2.0%

4.5%

Cardiac insufficiency

9.0%

10.1%

8.1%

8 (4.0%)

8 (4.6%)

1.0%

1.3%

Cerebral ischemia/Chronic stroke

9.0%

7.3%

10.3%

2 (1.0%)

4 (2.3%)

0.0%

0.1%

Neuropathies

8.2%

8.1%

8.2%

7 (3.5%)

6 (3.4%)

4.6%

3.9%

Renal insufficiency

6.5%

4.2%

8.3%

4 (2.0%)

9 (5.2%)

0.0%

2.6%

Cardiac valve disorders

5.7%

5.2%

6.0%

4 (2.0%)

5 (2.9%)

0.1%

2.2%

No multimorbidity pattern

       

Severe vision reduction

20.6%

22.0%

19.6%

3 (1.5%)

2 (1.1%)

0.1%

0.0%

Cancers

18.4%

14.8%

21.2%

-

2 (1.1%)

-

0.0%

Urinary incontinence

5.1%

7.1%

3.5%

2 (1.0%)

2 (1.1%)

0.0%

0.0%

  1. ADS: Anxiety, depression and somatoform disorders; PAOD: peripheral arterial occlusive disease; COPD: chronic obstructive pulmonary disease; GERD: gastro-esophageal reflux disease; *gender-specific disease.