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Table 4 Summary of the type and quality of evidence for mortality outcomes

From: Time to initiation of breastfeeding and neonatal mortality and morbidity: a systematic review

No of Studies

Design

Mortality outcome*

Consistency

Generalizability (location)

Relative Risk (95% CI)

Grade

Comments

3

prospective cohort studies

All causes, among all live births

marginal heterogeneity from meta analysis (p=0.076); all studies show a benefit

South Asia, West Africa

0.56 (0.40 – 0.79)

 

Random effects meta analysis

3

prospective cohort studies

All causes, among low birth weight babies

Q test for heterogeneity from meta analysis (p=0.585); two of three studies show a benefit

South Asia, West Africa

0.58(0.43 – 0.78)

 

Random effects meta analysis

3

prospective cohort studies

Infection-related causes, among all live births

Q test for heterogeneity from meta analysis (p=0.134); one of three studies shows a benefit

South Asia, West Africa

0.55 (0.36 – 0.84)

 

Random effects meta analysis

3

prospective cohort studies

Sepsis-specific mortality, among all live births

Q test for heterogeneity from meta analysis (p=0.138); all studies show a benefit

South Asia, West Africa

0.42 (0.23 – 0.74)

 

Random effects meta analysis

3

prospective cohort studies

Birth asphyxia-specific mortality, among all live births

Q test for heterogeneity from meta analysis (p=0.887); zero of three studies show a benefit

South Asia, West Africa

0.50 (0.23 – 1.12)

 

Random effects meta analysis

2

prospective cohort studies

Prematurity-specific mortality, among all live births

Q test for heterogeneity from meta analysis (p=0.418); one of two studies show a benefit

South Asia, West Africa

0.56 (0.30, 1.02)

 

Random effects meta analysis