Table 1 Univariable and multivariable logistic regression of the association between age at diagnosis and other factors with late presentation
From: Older HIV-infected individuals present late and have a higher mortality: Brighton, UK cohort study
N = 1536 | Late presenters N (%) | Early presenters N (%) | Crude odd ratios (95% CI) | p -value | Multivariable odd ratios (95% CI) | p -value |
|---|---|---|---|---|---|---|
Age | <0.001 | <0.001 | ||||
<50 | 658(47.5) | 727(52.5) | 1 | 1 | ||
>50 | 96(63.6) | 55(36.4) | 1.93(1.36-2.73) | 2.18(1.52-3.12) | ||
Ethnicity | <0.0001 | <0.0001 | ||||
Caucasian | 540 (44.2) | 681(55.8) | 1 | 1 | ||
African/Caribbean | 170(71.1) | 69(28.9) | 3.10(2.30-4.20) | 2.64(1.75-3.97) | ||
Others | 35(54.7) | 29(45.3) | 1.52(0.92-2.52) | 1.57(0.93-2.64) | ||
Unknown | 9(75.0) | 3(25.0) | 3.78(1.02-14.04) | 3.30(0.86-12.65) | ||
Sex/Risk group | ||||||
MSM | 493(43.5) | 641(56.5) | 1 | <0.0001 | 1 | 0.004 |
Female heterosexual | 137(63.7) | 78(36.3) | 2.28(1.69-3.09) | 1.27(0.85-1.90) | ||
Male heterosexual | 117(68.8) | 53(31.2) | 2.87(2.03-4.05) | 2.00(1.37-2.93) | ||
Others | 7(41.2) | 10(58.8) | 0.91(0.34-2.41) | 0.89(0.33-2.43) | ||
Calendar period | 0.005 | 0.002 | ||||
1996-2001 | 220(54.5) | 181(45.1) | 1 | 1 | ||
2002-2005 | 282(49.8) | 284(50.2) | 0.82(0.63-1.06) | 0.72(0.55-0.94) | ||
2006-2010 | 252(44.3) | 317(55.7) | 0.65(0.51-0.85) | 0.62(0.48-0.81) |