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The double task of preventing malnutrition and overweight: a quasi-experimental community-based trial
© Navarro et al.; licensee BioMed Central Ltd. 2013
Received: 11 July 2012
Accepted: 4 March 2013
Published: 9 March 2013
The Maternal-Child Pastoral is a volunteer-based community organization of the Dominican Republic that works with families to improve child survival and development. A program that promotes key practices of maternal and child care through meetings with pregnant women and home visits to promote child growth and development was designed and implemented. This study aims to evaluate the impact of the program on nutritional status indicators of children in the first two years of age.
A quasi-experimental design was used, with groups paired according to a socioeconomic index, comparing eight geographical areas of intervention with eight control areas. The intervention was carried out by lay health volunteers. Mothers in the intervention areas received home visits each month and participated in a group activity held biweekly during pregnancy and monthly after birth. The primary outcomes were length and body mass index for age. Statistical analyses were based on linear and logistic regression models.
196 children in the intervention group and 263 in the control group were evaluated. The intervention did not show statistically significant effects on length, but point estimates found were in the desired direction: mean difference 0.21 (95%CI −0.02; 0.44) for length-for-age Z-score and OR 0.50 (95%CI 0.22; 1.10) for stunting. Significant reductions of BMI-for-age Z-score (−0.31, 95%CI −0.49; -0.12) and of BMI-for-age > 85th percentile (0.43, 95%CI 0.23; 0.77) were observed. The intervention showed positive effects in some indicators of intermediary factors such as growth monitoring, health promotion activities, micronutrient supplementation, exclusive breastfeeding and complementary feeding.
Despite finding effect measures pointing to effects in the desired direction related to malnutrition, we could only detect a reduction in the risk of overweight attributable to the intervention. The findings related to obesity prevention may be of interest in the context of the nutritional transition. Given the size of this study, the results are encouraging and we believe a larger study is warranted.
In 2008, a group of researchers produced a series of articles drawing the attention of national policymakers and the international community to put in place and maintain effective programs to fight mother and child undernutrition among the priorities for achieving several of the Millennium Development Goals . It is estimated that the joint effect of the main indicators of child undernutrition and sub-optimum breastfeeding practices accounts for 35% of the deaths of children under 5 years of age worldwide . Among the survivors, important sequelae remain; the long term consequences most strongly associated to undernutrition during the first years of age include: shorter adult height, less schooling, reduced economic productivity, and lower offspring birth weight in women . The analysis of representative data from less economically developed countries shows that the phenomenon of growth faltering takes place during the first years of life, and then it stabilizes . The nutritional recovery of children who were malnourished during their first years of life fails to avoid important consequences, and a fast weight gain of these children in the following years can increase the risk of cardiovascular and metabolic diseases in adulthood . It is therefore clearly necessary to implement programs aimed at preventing undernutrition since pregnancy and during the child’s first years of life.
During the past few decades important progress has been made in the reduction of child undernutrition in developing countries. In Latin America and the Caribbean, the prevalence of stunting dropped by 44% between 1980 and 2000 . Nevertheless, this progress has been very unequal both at the regional level and within each country, as child undernutrition persists, although it is a high priority. On the other hand, as the fight against undernutrition advances, the problem of obesity emerges at a quite accelerated pace . For example, in the Dominican Republic, although the goal of halving low weight-for-age among children under 5 was quickly achieved (10.4% in 1991 vs 5.3% in 2002) [7, 8], the prevalence of weight-for-height greater than +2 standard deviations increased from 2.8% in 1991 to 6.5% in 2002 . It is estimated that the prevalence of obesity among adults in this country will increase from 16.9% in 2002 to 30.5% by 2015 .
Thus, it is urgent to develop large-scale interventions addressed at promoting a more healthy nutritional transition in low-income and middle-income countries, reducing undernutrition while preventing the increase of incidence of chronic diseases related to the excess of weight .
Systematic reviews have detected the positive effect of community lay health workers in promoting child health practices such as immunization and breastfeeding, however they did not find evidence of an effect on nutritional status [11, 12]. Studies on the impact of a volunteer community health worker program (Child Pastoral Program) in Brazil did not find effect on stunting [13, 14]. Nonetheless some of the intervention on complementary feeding practices delivered to mothers by community workers have had positive effect on infant growth [15, 16].
In the Dominican Republic, the Maternal-Child Pastoral, a volunteer community organization, has designed a community intervention to improve integrated health and development during early childhood. The previous experience of the Brazilian Child Pastoral Program was adapted and the following actions have been added to improve the effect on child’s nutritional status: to start the intervention during pregnancy; to create guidelines for mother group meetings; to create guidelines to help nutritional counseling that take into account the trends in child’s growth curve; to deliver educative material to mothers about complementary feeding; to counsel about iron and vitamin A supplementation, including the dispensation of supplements in case local health facilities had not done before.
Among the objectives of the intervention are the reduction of both malnutrition and the risk of overweight in the first two years of age. This intervention was first implemented as a pilot in mid 2004 in coordination with the local offices of the Pan-American Health Organization (PAHO/WHO), the United Nations Children’s Fund (UNICEF), the Ministry of Public Health of the Dominican Republic, and the National Breastfeeding Commission within the family and community component of the Integrated Management of Childhood Illness (IMCI) strategy. This study tests the hypothesis that children participating in the Mother-Child Pastoral from pregnancy would have better nutritional indicators in respect both to stunting and overweight, in the second year of age, compared to children in communities of similar socioeconomic conditions where the program does not exist.
According to the causal model proposed by UNICEF on the factors affecting child survival, growth, and development , this intervention acts on an intermediary level by means of an educative process which tries to modify mother and child care practices. Taking as a reference the key family practices of the IMCI [18, 19] a strategic decision was made to start the intervention from the key practice that aims an adequate antenatal care. The first step was to create groups of pregnant women which met every fifteen days according to protocols defined in ten educational meetings on health and nutrition during pregnancy. Simultaneously to these meetings were held monthly home visits. Fortnightly home visits were carried out during the first month and a half after child birth in order to support breastfeeding and newborn care. Thereafter, group meetings and semi-structured home visits were carried out once every month to deal with breastfeeding, vaccination, newborn care, danger signs, complementary feeding, micronutrient supplementation, prevention and treatment of infectious diseases, growth monitoring, early stimulation, and prevention of accidents.
The educational process was based on a concept of transformational education similar to the decision-making process known as Triple A (assessment-analysis-action) proposed by UNICEF and WHO . The education agents are community volunteers known as community counselors (most of whom are women with the same formal education profile as the mothers benefited), who participate in a 60-hour basic training facilitated by health professionals previously trained in key practices of the IMCI community component.
As part of the intervention, the children’s physical growth was monitored at the monthly meetings of mothers (or during the home visits) to check the progress on their weight-for-age curve. The children were weighed by the community counselors using spring scales provided by the UNICEF Supply Division. The measures were plotted along the NCHS growth charts for assessing the trend of the child’s weight-for-age curve. Based on this evaluation, the counselors followed an advice protocol called Nutritional Advice Based on the Growth Curve. This protocol included recommendations to enhance caloric density, frequency and/or quantity of food in the case that the trend of the curve showed insufficient weight gain and revision of inadequate practices of increased energetic ingestion in the event that the growth curve increased at a pace that led to overweight for age. When the deflection from the expected trend continued for more than two consecutive evaluations, the counselor referred the mother for evaluation by a health professional, and then resumed monitoring. The education materials were prepared based on reference documents and materials published by WHO/PAHO [20, 21] and the volunteer’s manual of the Child’s Pastoral in Brazil .
Community average wealth index in the study groups, according to the National Census 2002
24 de Abril
Bateyes Santa Fe
Parajes Ntra. Sra. de la Paz
Parajes Ntra. Sra. Consolación
Brisas de los Palmares
The primary outcome indicators selected for this study were: mean length-for-age Z-score (LAZ), prevalence of stunting (LAZ < −2), mean BMI-for-age Z-score (BAZ) and prevalence of BMI-for-age > 85th percentile, defined as “at risk for overweight.”
The sample size was calculated for a one-tailed test considering that the intervention could either improve the health and nutrition indicators or have no effect on them, but it could not worsen them . The confidence level established was 95% and the statistical power 80%. With the information available at the time of the intervention design , and with data previously collected in a few communities in which the intervention was going to be conducted, a 20% for stunting was taken as reference for the child population aged 12–23 months. With a sample size of 283 in each group (intervention-control) it would be possible to detect reductions by 40% in the prevalence of stunting. Considering 10% of loss during monitoring, 312 cases would be allocated in each group.
The questionnaires were applied by medical students, as part of a course in epidemiology, and the anthropometrists were previously standardized . For practical reasons it was not feasible to conduct a double-blind study.
Databases were prepared using Epi Info, version 3.2 for Windows (Center for Disease Control and Prevention, Atlanta, GA, USA). After a double-entry procedure, typing errors were identified and corrected using the Epi Info “Data Compare” module. Later revisions for amplitude and consistency were administered.
For anthropometric measurements, mother/child electronic scales with a precision of 0.1 Kg (UNISCALE, UNICEF Supply Division) and Shorr length measuring boards accurate to 0.1 cm (Shorr Productions Growth Unlimited, Olney, Md., USA) were used. Measurements were made according to procedures recommended by the World Health Organization [31, 32], and the average measure of two standardized anthropometrists was used, repeating up to twice whenever the difference between both was over 0.7 cm or 0.1 Kg . The anthropometric indexes were calculated by WHO Anthro 2005 software, using the new WHO Child Growth Standards.
Since the intervention was allocated according to geographic areas, multilevel analysis were conducted to evaluate the presence of nested random effects on the main results, taking into consideration the interdependency between children from a same branch and a same community. However, for the regression models of the primary outcomes LAZ, LAZ < −2, BAZ and BMI-for-age > 85th percentile, at the final assessment, there was no significant intraclass correlation and the multilevel models were not different from the traditional ones when compared through the likelihood ratio test. Therefore, it was decided that the analysis would be made without resorting to the multilevel model techniques. Two-tailed tests were used.
Baseline data between the study groups were compared using chi-square test for categorical variables and t test for continuous. In assessing the effect of the intervention on the outcomes, multivariate linear regression models were performed for adjustment in relation to all potential confounding factors that had p<0.10 in the model.
All of these analyses were conducted with Stata, version 10.0 (Stata Corp. LP, College Station, TX, USA).
Loss of follow-up
Given the high mobility of the studied population it was not possible to measure the outcome variables in those subjects that were lost during the study. To assess whether these individuals differed from those who were followed up to the end, statistical analyses were carried out comparing baseline data.
The study was approved by the Committee of Ethics in Research of the Federal University of São Paulo and was implemented in coordination with the Ministry of Public Health of the Dominican Republic. Mothers were asked to sign a written consent. In both intervention and control groups malnourished children were referred to the specific health service.
Figure 1 shows the flow of participants through the study . After about a year and a half of follow-up the intervention group lost 26% of its subjects and the control group lost 22%. The main cause for this was changing the place residence. The number of analyzed subjects was 193 in the intervention group and 259 in the control group. After comparing 16 baseline variables between the lost-of-follow-up subjects and the completely-followed-up ones (see Additional file 1), it was found that within the intervention group lost-of-follow-up mothers were younger (21.3 vs 24.1 years) and their children were more frequently first born (42.5% vs 28.5%). Within the control group lost-of-followed-up mothers had a lower household wealth index (43.01 vs 49.43) and more frequently disposed waste in a nearby dump, river or glen (48.5% vs 33.9%).
Baseline data according to study group
Final child’s age, months b c
19.74 ± 2.08
20.32 ± 1.70
Sex of the child
Maternal education, years b
Paternal education, years b
Household wealth index c
49.43 ± 20.55
50.54 ± 19.14
Household income, minimum wage per month
Mother had worked in the last 12 months b d
Permanent economic support from father b
Mother possesses “Comer es primero” card b e
National origin of the mother
Piped water inside the house (or outside, rural)
Waste disposed in a nearby dump, river or glen
More than 2 children aged 0–4 in the household
Father lives in the house with mother b
Maternal height, cm c
159.12 ± 6.43
159.03 ± 6.06
Maternal BMI, kg/m2 f
22.46 ± 1.20
22.27 ± 1.20
Maternal age, years f
23.28 ± 1.26
24.08 ± 1.26
First born child
Desire for pregnancy
Wanted to become pregnant at the time
Wanted to wait or did not want more children
Birthweight, kg c
3.20 ± 0.59
3.18 ± 0.55
Low birthweight (< 2.5 kg)
The results of the anthropometric indicators revealed a low prevalence of wasting (weight-for-length Z-score < −2) both in the control group and in the intervention group, respectively 1.16% and 2.07%, with no significant difference (P=0.436). These prevalence values are within the expected range in the WHO standard population and are close to the findings of the 2007 Dominican Republic Demographic and Health Survey  (2.2% for children younger than five). In the same survey, the prevalence of low weight-for-age in children under 5 was 3.1%; in our study it was 3.86% in the control group and 2.07% in the intervention group, a difference that lacks statistical significance (P=0.278).
Effect of the intervention on anthropometric indicators
n = 259
n = 193
x ± SD
x ± SD
Δ x (CI 95%)
Δ x (CI 95%)
Length-for-age (Z score) a
−0.66 ± 1.09
−0.46 ± 1.21
0.20 (−0.01; 0.41)
0.21 (−0.02; 0.44)
BMI-for-age (Z score) b
0.35 ± 0.92
0.13 ± 0.94
−0.22 (−0.40; -0.05)
−0.31 (−0.49; -0.12)
OR (95% CI)
OR (95% CI)
Stunting (LAZ < −2) c
0.58 (0.30; 1.11)
0.50 (0.22; 1.10)
Risk of overweight (BMI-for age > 85th percentile)d
0.64 (0.39; 1.04)
0.43 (0.23; 0.77)
The mean BMI-for-age Z-score was 35 ± 0.92 in the control group and 0.13 ± 0.94 in the intervention group, with an adjusted effect of −0.31 (P=0.001). The categorical analysis of this variable found a difference in the proportion of children with BMI-for-age > 85th percentile, with values of 22.39% in the control group and 15.54% in the intervention group, with an adjusted odds ratio of 0.43 and confidence interval between 0.23 and 0.77 (P=0.005). To obtain the figures of this effect in terms of prevalence ratio, the same model was applied using Poisson regression with robust variance , which led to a prevalence ratio of 0.52, indicating a reduction by 48% in the proportion of children with risk of overweight. On the other hand, when the Z-score with cut-off point +2 was considered instead of 85th percentile, the resulting prevalence was 3.47% in the control group and 1.55% in the intervention group (P=0.209).
Intermediary factors – health promotion, feeding practices and disease prevention and treatment
Indicator of the intermediary factor
n = 259
n = 193
OR (95% CI)
Child was weighed in the last 4 months
4.64 (2.95; 7.32)
The child growth curve was explained to the mother
6.45 (4.24; 9.80)
Mother received counseling on infant and young child feeding practices in the last 4 months
11.19 (7.02; 17.82)
Mother received a home visit from a community health agent or health professional in the last 4 months
16.41 (10.06; 26.77)
Mother participated in child health and nutrition meeting since the child’s birth
311.9 (108.5; 896.5)
Mother took a Vitamin A capsule in the 8 weeks following birth
8.45 (5.45; 13.11)
Exclusive breastfeeding through 6 months of age
3.28 (1.24; 8.69)
Predominant breastfeeding through 6 months of age c
3.60 (1.83; 7.09)
Child currently breastfeeding
0.97 (0.63; 1.49)
Child received 5 or more feedings with solid or semisolid foods in the last 24 hours
1.62 (1.03; 2.55)
Child consumed foods rich in vitamin A in the last 24 hours d
0.92 (0.59; 1.41)
Child consumed fruits in the last 24 hours
1.52 (1.02; 2.26)
Child received vitamin A supplement
2.35 (1.49; 3.71)
Child received iron supplement in the last 3 months
8.23 (5.07; 13.37)
Disease prevention and treatment
Child consumed water from the faucet, not boiled, without chlorine
0.48 (0.28; 0.85)
with greatest frequency
Child used bottle in the last 24 hours
0.79 (0.51; 1.23)
Child had diarrhea in the last 2 weeks
0.99 (0.59; 1.67)
Child received more liquids during diarrhea
3.42 (1.06; 11.07)
Child received ORS during diarrhea
3.86 (1.14; 13.02)
Child received equal or greater amount of foods during diarrhea
0.63 (0.24; 1.66)
Mother mentioned a sign of emergency during diarrhea
1.67 (1.10; 2.54)
Child completed vaccination schedule in the first year of life
2.00 (1.37; 2.94)
Child was hospitalized in the last 12 months
1.09 (0.70; 1.68)
The results related to some of the feeding practices show a higher consumption of vitamin A and iron supplements by children and mothers in the intervention group. When mothers were asked about the age that child started receiving regularly the food items from a list, the prevalence of exclusive breastfeeding was shown to be 2.34% in the control group and 7.29% in the intervention group (P=0.017). On the other hand, in the intervention group there was a higher proportion of children that consumed five or more solid or semisolid food items over the past 24 hours (27.46% vs 18.53% in the control group, P=0.037). However, there was no difference either in the consumption of vitamin A rich food or in most of the particular food items in the previous 24 hours or in the previous 7 days.
Table 4 also shows the results of some factors related to the prevention and treatment of illness. Differences were found that indicate more adequate practices in the intervention group related to immunization, drinking water and administration of liquids and oral rehydration salts during diarrhea. However, there was no difference between the groups with regard to the use of bottle and the amount of food consumed during diarrhea. Neither were there any differences between the groups with regard to the prevalence of diarrhea over the past two weeks or in the proportion of children hospitalized during the past 12 months.
The results of this study show that the intervention was associated with a lower risk of overweight. The approximation of the mean Z score of this index towards the value corresponding to the WHO reference population (Z = 0), with a decrease in the proportion of children with a score above the 85th percentile without causing an increase in wasting, points to a healthy decrease in the risk of overweight. The size of the adjusted effect (OR = 0.43) is equivalent to a decrease by nearly 48% in relation to the prevalence in the control group. This effect is important under the preventive point of view; children with body mass index over 85th percentile during early childhood have a high probability of being overweight in adolescence [37, 38].
Since the study aimed to analyze not only the effect on nutritional indicators but also on various health aspects that the intervention intended to modify (within the integrated approach of the IMCI), no data were collected on some intermediary factors that could have explained better the causal pathway of the effects on overweight. However, the results observed in the activities related to growth monitoring, coupled with the fact that the nutritional counseling protocols included clear instructions about what issues should be discussed with the mother when the weight-for-age curve had a tendency towards the overweight-for-age zone, support the plausibility of attributing these results to the intervention.
As expected in impoverished communities, the mean length-for-age Z-score (LAZ) in both groups was below the corresponding level at the WHO reference population. The intervention did not show statistically significant effects on length, but point estimates found were in the desired direction, with a mean difference of 0.21, which is similar to that found in other educational interventions. In a recent review study carried out by Imdad et al. , eight studies were selected that evaluated interventions based on maternal education regarding complementary feeding, without the provision of food, resulting in a positive effect in linear growth with a weighted mean difference of 0.21.
A limitation on the probabilistic analysis of the effect of the intervention on the prevalence of stunting was the sample size. It was calculated for a one-tailed test based on an expected prevalence of 20% in the control group, while the found value was 12%. For the magnitude of the intervention effect that was found, it would have required a larger sample size for a significance level of 95%. Furthermore, the sample size calculation did not take into account the clustering.
Our study found positive effect in several indicators of intermediary factors. Whereas in the control group there was a gradual decrease in action regarding growth monitoring, falling from 51% of children weighed in the past 4 months to 28% in cases where an explanation was given to the mother about the results of the curve, up to 18% receiving feeding advice, the intervention group showed another profile: 83% of the children had been weighed and approximately 70% of the mothers had received both explanations about the growth curve and child feeding advice. The intervention performed by the lay health volunteers showed also significant effects in micronutrient supplementation. The proportion of children supplemented with vitamin A capsules and with ferrous sulfate drops was higher in the intervention group, thus resulting in a lower prevalence of anemia, with adjusted odds ratio of 0.57 (P=0.011) for Hb < 11.0 g/dl and 0.46 (P<0.001) for Hb < 10.0 g/dl (article in preparation). As we expected, effects on food consumption were not as positive as those on micronutrients consumption. Nevertheless there was an increase in exclusive breastfeeding and in the proportion of children who had consumed 5 or more solid food portions in the last 24 hours.
Upon reviewing the eight studies analyzed by Imdad et al. , we observed that none of them evaluated the possible effect of the intervention with regard to overweight. In the context of nutritional transition in low-income and middle-income countries, we can consider that the principal contribution of our study is to integrate the prevention of children becoming overweight in an intervention program focused primarily on preventing malnutrition. Furthermore, in current scientific literature regarding interventions where the primary goal is the prevention of childhood obesity, there are very few intervention studies that focus on the first two years of age . In a recent systematic review about interventions to prevent obesity among children aged 0–5 years, seven of twenty-five studies had included younger than 2 years of age, but just two had reported anthropometric measurements, one of them finding a positive trend towards overweight prevention . Another contribution from this present study is that its results suggest that in situations in which body-mass-index is difficult to be periodically assessed early intervention to prevent overweight can be based on monitoring the weight-for-age.
The outcomes were assessed against the WHO Child Growth Standards, while during the intervention the mothers were given feeding advice based on plotting the child’s growth against NCHS weight-for-age charts due to the fact that until then the new standards had not been adopted. As the average weight of infants included in the WHO standards was above the NCHS median during their first six months of life, and thereafter continued below , we can deduce that during the intervention there was a tendency to be less demanding in controlling risk of underweight in the first six months (when the NCHS references identify lower prevalence of underweight than WHO standards) and be more demanding in this matter after seven months (when NCHS references identify higher prevalence of underweight than WHO standards). Opposite trends would be present in regards to control the risk of higher than expected weight for age. We could think that these tendencies due to differences between the WHO standards and NCHS references were diminished during the intervention by the fact that counseling protocols oriented to act not only when achieving the cutoffs level of underweight or high weight for age, but also by observing early trends of diversion of the curve.
Among the limitations of this study is included the fact that we did not use an intention to treat analysis, due to difficulties to gather the outcome data in the missing cases. This weakens its external validity in regards to public health policies, as their conclusions are applicable on the condition of the families remaining in the intervention process. Loss of follow-up after allocation is a frequent limitation in public health program studies. In this research, women who dropped out differed from those who remained in the study in 2 of 16 baseline variables analyzed in the intervention group, and in 2 variables in the control group. These differences did not negatively affect the homogeneity of the study groups among the remaining cases.
Furthermore, although important intervention performance indicators were used regarding the last four months of the intervention, it would have been important to evaluate some other longitudinal indicators besides the number of meetings attended by mothers, for example, the number of home visits received since the beginning of intervention. It would have also been desirable to use other indicators related to fidelity of volunteers to the intervention protocols. Another limitation of the study consists that the assessors could not be blind in regards to the allocation of the participants, since it was practically impossible not to recognize when a participant of the study was also a participant of the intervention group. To reduce bias, interviewers had not taken part in the intervention and were trained using proper instruction manual for their questionnaires. Anthropometry assessment followed standardized procedures.
In this study, the provision of the intervention and the adhesion of the beneficiaries have not been controlled to ensure the ideal compliance of the protocols. However, the participation of the team that designed the intervention and its evaluation implies a higher degree of stimulation in the provision of the intervention than there would be in routine conditions in a larger scale. Thus, this could be classified as a public health “program efficacy study” in the typology of evaluation studies proposed by Victora et al.  taking into account the level of control exercised on the dose in which the intervention would reach the beneficiaries. We thus have to place the findings of this research in an intermediary level between that of a “regime efficacy study” (in which the impact of the intervention tends to be greater) and that of a “program effectiveness study” in routine conditions (in which the impact of the intervention tends to be smaller). In the pair-matched design, in which a control area with similar socioeconomic conditions was assigned to each geographic area (branch) of intervention, the analysis of about twenty variables, following a hypothetical causal model, showed great homogeneity in the baseline characteristics of both studied groups. The variables in which there were differences were taken into account to build statistical models that allowed the adjustment of the analysis of the intervention effect with regard to possible confounding effects. This brings the design used closer to the benefits that would have a cluster randomized design.
Despite finding effect measures pointing to effects in the desired direction related to malnutrition, we could only detect a reduction in the risk of overweight attributable to the intervention. The findings related to obesity prevention may be of interest in the context of the nutritional transition. Given the size of this study, the results are encouraging and we believe a larger study is warranted. These results draw attention to the potential of community interventions carried out by lay volunteers, with an integral approach since pregnancy, to achieve important progress in the double task of preventing undernutrition and obesity, as part of the development process in low-income and middle-income countries.
The intervention and the impact assessment were carried out with financial support from the United Nations Children’s Fund (UNICEF), the Ministry of Public Health of the Dominican Republic, private donors from the Netherlands, and the partnership Action for Family Health (Catholic Medical Mission Board, Pan-American Health Organization (PAHO/WHO), Brystol-Myers Squibb Foundation). We also thank the Child’s Pastoral of Brazil for the support to learn and adapt their methods of intervention, the Graduate Program in Nutrition -Federal University of São Paulo- for their assistance in designing the intervention and the Graduate Program in Epidemiology -Federal University of Pelotas- for his key contributions in methodological aspects of the impact assessment. Special thanks to the families participating in the study, volunteers and professional staff of the Maternal-Child Pastoral, and all persons and institutions who contributed to this work.
- Bryce J, Coitinho D, Darnton-Hill I, Pelletier D, Pinstrup-Andersen P, for the Maternal and Child Undernutrition Study Group: Maternal and child undernutrition: effective action at national level. Lancet. 2008, 371: 510-526. 10.1016/S0140-6736(07)61694-8.View ArticlePubMedGoogle Scholar
- Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, Mathers C, Rivera J, for the Maternal and Child Undernutrition Study Group: Maternal and child undernutrition: global and regional exposures and health consequences. Lancet. 2008, 371: 243-260. 10.1016/S0140-6736(07)61690-0.View ArticlePubMedGoogle Scholar
- Victora CG, Adair L, Fall C, Hallal PC, Martorrel R, Richter L, Sachdev HS, for the Maternal and Child Undernutrition Study Group: Maternal and child undernutrition: consequences for adult health and human capital. Lancet. 2008, 371: 340-357. 10.1016/S0140-6736(07)61692-4.View ArticlePubMedPubMed CentralGoogle Scholar
- Victora CG, de Onis M, Hallal PC, Blössner M, Shrimpton R: Worldwide timing of growth faltering: revisiting implications for interventions. Pediatrics. 2010, 125: e473-e480. 10.1542/peds.2009-1519.View ArticlePubMedGoogle Scholar
- Pan-American Health Organization: Salud en Las Américas 2007. 2008, Washington, D.C: OPS, 263-266. Publicación Científica y Técnica No. 622Google Scholar
- Popkin BM, Adair LS, Ng SW: Global nutrition transition and the pandemic of obesity in developing countries. Nutr Rev. 2012, 70: 3-21. 10.1111/j.1753-4887.2011.00456.x.View ArticlePubMedPubMed CentralGoogle Scholar
- Instituto de Estudios de Población y Desarrollo (IEPD): Encuesta demográfica y de salud República Dominicana 1991. 1992, Santo Domingo: IEPD, ONAPLANGoogle Scholar
- Molina M, Ramírez N, Polanco JJ, Ochoa LH, Lerebours G, García B: Encuesta demográfica y de salud República Dominicana 2002. 2003, Santo Domingo: CESDEM, ORC Macro/ MEASURE DHS+Google Scholar
- World Health Organization: WHO Global database on child growth and malnutrition. [http://www.who.int/nutgrowthdb/database/countries/dom/en/]
- World Health Organization: WHO Global Infobase. [https://apps.who.int/infobase/Indicators.aspx]
- Lipp A: Lay health workers in primary and community health care for maternal and child health and the management of infectious diseases: a review synopsis. Public Health Nurs. 2011, 28: 243-245. 10.1111/j.1525-1446.2011.00950.x.View ArticlePubMedGoogle Scholar
- Glenton C, Scheel IB, Lewin S, Swingler GH: Can lay health workers increase the uptake of childhood immunisation? Systematic review and typology. Trop Med Int Health. 2011, 16: 1044-1053. 10.1111/j.1365-3156.2011.02813.x.View ArticlePubMedGoogle Scholar
- Neumann NA, Victora CG, Halpern R, Guimarães PR, Cesar J: Desempenho da Pastoral da Criança na promoção de ações de sobrevivência infantil e na educação em saúde em Criciúma, uma cidade do sul do Brasil. Rev Panam Salud Publica. 1999, 5: 400-410. 10.1590/S1020-49891999000500004.View ArticlePubMedGoogle Scholar
- Neumann NA, Victora CG, Valle NJ, Cesar JA, Horta BL, Lima SM, Barros FC: Impacto da Pastoral da Criança sobre a nutrição de menores de cinco anos no Maranhão: uma análise multinivel. Rev Bras Epidemiol. 2002, 5: 30-40. 10.1590/S1415-790X2002000100005.View ArticleGoogle Scholar
- Guldan GS, Fan HC, Ma X, Ni ZZ, Xiang X, Tang MZ: Culturally appropriate nutrition education improves infant feeding and growth in Rural Sichuan, China. J Nutr. 2000, 130: 1204-1211.PubMedGoogle Scholar
- Bhandari N, Mazumder S, Bahl R, Martines J, Black RE, Bhan MK, for the Infant Feeding Study Group: An educational intervention to promote appropriate complementary feeding practices and physical growth in infants and young children in Rural Haryana, India. J Nutr. 2004, 134: 2342-2348.PubMedGoogle Scholar
- United Nations Children’s Fund: Strategy for improved nutrition of children and women in developing countries. 1990, New York: UNICEFGoogle Scholar
- World Health Organization: Child health in the community; community IMCI: briefing package for facilitators: reference document. 2004, Geneva: WHO, v. 1-Google Scholar
- Hill Z, Kirkwood B, Edmond K: Family and community practices that promote child survival, growth and development: a review of the evidence. 2004, Geneva: WHOGoogle Scholar
- World Health Organization: Handbook IMCI, Integrated Management of Childhood Illness. 2000, Geneva: WHOGoogle Scholar
- Organization Pan-American Health: Guiding principles for complementary feeding of the breastfed child. 2002, Washington D.C: PAHO/ WHOGoogle Scholar
- da Criança Pastoral: Guia do Líder da Pastoral da Criança. 2000, Curitiba: Pastoral da Criança, 2aGoogle Scholar
- Rutstein SO, Kiersten J: The DHS Wealth Index. 2004, Maryland: ORC Macro, (DHS Comparative Reports No. 6)Google Scholar
- Molina M, Polanco JJ: Encuesta por conglomerados de indicadores multiples (MICS–2000). 2001, Santo Domingo: Fondo de las Naciones Unidas para la Infancia / Secretariado Técnico de la Presidencia, [http://www.childinfo.org/files/dominicanrep.pdf ]Google Scholar
- Victora CG, Bryce J, Martines JC, Habicht JP, Phillips M: Evaluation of the Impact of Integrated Management of Childhood Illness. Design Issues. 1998, Geneva: World Health Organization, [http://www.who.int/imci-mce/Publications/IMCI_Design.pdf]Google Scholar
- World Health Organization (WHO): Household Survey. WHO. Multi-Country Evaluation of IMCI. [http://who.int/imci-mce/Methods/household_survey.htm]
- Cesar JA, Gonçalves TS, Neumann NA, Oliveira JA, Diziekaniak AC: Saúde infantil em áreas pobres das regiões Norte e Nordeste do Brasil: comparando indicadores básicos em áreas atendidas pela Pastoral da Criança e áreas controle. Cad Saude Publica. 2005, 21: 1845-1855. 10.1590/S0102-311X2005000600034.View ArticlePubMedGoogle Scholar
- Santos I, Victora CG, Martines J, Gonçalves H, Gigante DP, Valle NJ, Pelto G: Nutrition counseling increases weight gain among Brazilian children. J Nutr. 2001, 131: 2866-2873.PubMedGoogle Scholar
- Centro de Estudios Sociales y Demográficos (CESDEM): Encuesta demográfica y de salud República Dominicana 1996. 1997, Santo Domingo: CESDEM, PROFAMILIA, ONAPLAN, DHS/Macro InternationalGoogle Scholar
- World Health Organization: Medición del cambio del estado nutricional. 1983, Geneva: WHOGoogle Scholar
- United Nations Department of Technical Co-operation for Development and Statistical Office: How to Weigh and Measure Children: Assessing the Nutritional Status of Young Children in Household Surveys. 1986, New York: United NationsGoogle Scholar
- World Health Organization: Anthropometry training video. [http://www.who.int/childgrowth/training/en/]
- De Onis M, Onyango AW, Van den Broeck J, Chumlea WC, Martorell R: Measurement and standardization protocols for anthropometry used in the construction of a new international growth reference. Food Nutr Bull. 2004, 25 (suppl 1): S27-S36.View ArticlePubMedGoogle Scholar
- Des Jarlais DC, Lyles C, Crepaz N, TREND Group: Improving the reporting quality of nonrandomized evaluations of behavioral and public health interventions: the TREND statement. Am J Public Health. 2004, 94: 361-366. 10.2105/AJPH.94.3.361.View ArticlePubMedPubMed CentralGoogle Scholar
- Centro de Estudios Sociales y Demográficos (CESDEM): Encuesta Demográfica y de Salud República Dominicana 2007. 2007, Santo Domingo: CESDEM, MEASURE DHS/ Macro InternationalGoogle Scholar
- Barros AJ, Hirakata VN: Alternatives for logistic regression in cross-sectional studies: an empirical comparison of models that directly estimate the prevalence ratio. BMC Med Res Methodol. 2003, 3: 21-10.1186/1471-2288-3-21.View ArticlePubMedPubMed CentralGoogle Scholar
- Nader PR, O’Brien M, Houts R, Bradley R, Belsky J, Crosnoe R, Friedman S, Mei Z, Susman EJ: Identifying risk for obesity in early childhood. Pediatrics. 2006, 118: e594-e601. 10.1542/peds.2005-2801.View ArticlePubMedGoogle Scholar
- Shankaran S, Bann C, Das A, Lester B, Bada H, Bauer CR, La Gasse L, Higgins RD: Risk for obesity in adolescence starts in early childhood. J Perinatol. 2011, 31: 711-716. 10.1038/jp.2011.14.View ArticlePubMedPubMed CentralGoogle Scholar
- Imdad A, Yakoob MY, Bhutta ZA: Impact of maternal education about complementary feeding and provision of complementary foods on child growth in developing countries. BMC Publ Health. 2011, 11 (Suppl 3): S25-10.1186/1471-2458-11-S3-S25.View ArticleGoogle Scholar
- Askie LM, Baur LA, Campbell K, Daniels LA, Hesketh K, Magarey A, Mihrshashi S, Rissel C, Simes J, Taylor B, Taylor R, Voysey M, Wen LM, for the EPOCH Collaboration Group: The Early Prevention of Obesity in Children (EPOCH) Collaboration – an Individual Patient Data Prospective Meta-Analysis. BMC Publ Health. 2010, 10: 728-Google Scholar
- Hesketh KD, Campbell KJ: Interventions to prevent obesity in 0–5 year olds: an updated systematic review of the literature. Obesity (Silver Spring). 2010, 18: S27-S35. 10.1038/oby.2009.429.View ArticleGoogle Scholar
- De Onis M, Onyango AW, Borghi E, Garza C, Yang H, for the WHO Multicentre Growth Reference Study Group: Comparison of the World Health Organization (WHO) child growth standards and the National Center for Health Statistics/WHO international growth reference: implications for child health programmes. Publ Health Nutr. 2006, 9: 942-947.View ArticleGoogle Scholar
- Victora CG, Habicht JP, Brice J: Evidence-based public health: moving beyond randomized trials. Am J Public Health. 2004, 94: 400-405. 10.2105/AJPH.94.3.400.View ArticlePubMedPubMed CentralGoogle Scholar
- The pre-publication history for this paper can be accessed here:http://0-www.biomedcentral.com.brum.beds.ac.uk/1471-2458/13/212/prepub
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