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Table 8 Associations of high socioeconomic position (compared to low) at four life stages with white cell count and its differentials, adjusted for agea and sex Chinese adults (≥50 years) from the Guangzhou Biobank Cohort Study, phase 3, 2006-2008 including complete cases only

From: Life-course origins of social inequalities in adult immune cell markers of inflammation in a developing southern Chinese population: the Guangzhou Biobank Cohort Study

  

White Blood Cell Count (109/L)

  

Granulocyte Cell Count (109/L)

 
 

N

Δ

95% CI

AIC

N

Δ

95% CI

AIC

Men and Women

        

Critical period Modelb

        

   Childhood

9683

-0.14

(-0.21, -0.07)

8769

9683

-0.10

(-0.15, -0.04)

4038

   Early Adult

9976

-0.35

(-0.42, -0.29)

8906

9976

-0.26

(-0.31, -0.21)

4018

   Late Adult

8808

-0.23

(-0.31, -0.15)

7901

8808

-0.19

(-0.25, -0.12)

3575

   Current

8332

-0.23

(-0.30, -0.16)

7446

8332

-0.17

(-0.23, -0.12)

3362

Accumulation Modelc

   

6327

   

2872

   0

7117

0

  

7117

0.00

  

   1

7117

-0.19

(-0.31, -0.07)

 

7117

-0.18

(-0.28, -0.08)

 

   2

7117

-0.38

(-0.50, -0.26)

 

7117

-0.30

(-0.40, -0.21)

 

   3

7117

-0.54

(-0.66, -0.42)

 

7117

-0.43

(-0.52, -0.33)

 

   4

7117

-0.53

(-0.69, -0.38)

 

7117

-0.42

(-0.55, -0.30)

 

Sensitive Periods Modeld

   

6299

   

2851

   Childhood

7112

-0.05

(-0.13, 0.03)

 

7112

-0.03

(-0.09, 0.04)

 

   Early Adult

7112

-0.35

(-0.44, -0.26)

 

7112

-0.25

(-0.32, -0.18)

 

   Late Adult

7112

-0.07

(-0.16, 0.02)

 

7112

-0.07

(-0.14, -0.002)

 

   Current

7112

-0.12

(-0.20, -0.05)

 

7112

-0.10

(-0.16, -0.03)

 

Fully Saturated Model e

7112

  

6310

7112

  

2864

  1. Abbreviations: CI Confidence Interval; AIC Akaike Information Criterion
  2. Bold numbers indicate P < 0.05 for coefficients or best fitting model for AICs
  3. * Test for interaction with sex significant at p < 0.05 level
  4. aAge in five year age groups. bEstimates for SEP at each individual life stage adjusted for age and sex but unadjusted for SEP at other life stages. cNumber of periods in high SEP adjusted for age and sex. dMutually adjusted for SEP at other life stages and adjusted for age and sex. eIncludes SEP at all four life stages and all possible interactions between all four measures of SEP. Also adjusted for age and sex