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Table 6 Associations of high socioeconomic position (compared to low) at four life stages with white cell count and granulocyte count, adjusted for agea, sex and lifestyle factors and body mass index in 9,981 Chinese adults (≥50 years) from the Guangzhou Biobank Cohort Study, phase 3, 2006-2008

From: Life-course origins of social inequalities in adult immune cell markers of inflammation in a developing southern Chinese population: the Guangzhou Biobank Cohort Study

  

White Blood Cell Count (109/L)

  

Granulocyte Cell Count (109/L)

 
 

Δ

95% CI

AIC

Δ

95% CI

AIC

Men and Women

      

Critical period Modelb

      

   Childhood

-0.13

(-0.19, -0.06)

8248

-0.09

(-0.14, -0.04)

3675

   Early Adult

-0.31

(-0.38, -0.24)

8206

-0.24

(-0.29, -0.18)

3631

   Late Adult

-0.20

(-0.27, -0.12)

8239

-0.17

(-0.23, -0.10)

3659

   Current

-0.20

(-0.27, -0.14)

8223

-0.16

(-0.21, -0.11)

3646

Accumulation Modelc

     

3611

   0

0

 

8186.0

0

  

   1

-0.19

(-0.29, -0.09)

 

-0.14

(-0.22, -0.06)

 

   2

-0.28

(-0.37, -0.18)

 

-0.21

(-0.29, -0.14)

 

   3

-0.40

(-0.50, -0.30)

 

-0.31

(-0.39, -0.23)

 

   4

-0.42

(-0.56, -0.29)

 

-0.35

(-0.45, -0.24)

 

Sensitive Periods Modeld

  

8185.9

  

3608

   Childhood

-0.06

(-0.13, 0.01)

 

-0.04

(-0.09, 0.02)

 

   Early Adult

-0.18

(-0.25, -0.10)

 

-0.14

(-0.20, -0.08)

 

   Late Adult

-0.08

(-0.16, 0.00)

 

-0.08

(-0.14, -0.02)

 

   Current

-0.12

(-0.20, -0.05)

 

-0.10

(-0.15, -0.05)

 

Fully Saturated Modele

  

8198

  

3624

  1. Abbreviations: CI Confidence Interval; AIC Akaike Information Criterion
  2. Bold numbers indicate P < 0.05 for coefficients or best fitting model for AICs
  3. aAge in five year age groups. bEstimates for SEP at each individual life stage adjusted for age, sex, smoking, alcohol use, and physical activity and body mass index but unadjusted for SEP at other life stages. cNumber of periods in high SEP adjusted for age, sex, smoking, alcohol use, and physical activity and body mass index. dMutually adjusted for SEP at other life stages and adjusted for age, sex, smoking, alcohol use, and physical activity and body mass index. eIncludes SEP at all four life stages and all possible interactions between all four measures of SEP. Also adjusted for age, sex, smoking, alcohol use, and physical activity