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Table 4 Associations of high socioeconomic position compared to low at four life stages with white cell count and granulocyte count, adjusted for agea, sex and lifestyle factors in 9,981 Chinese adults (≥50 years) from the Guangzhou Biobank Cohort Study, phase 3, 2006-2008

From: Life-course origins of social inequalities in adult immune cell markers of inflammation in a developing southern Chinese population: the Guangzhou Biobank Cohort Study

 

White Blood Cell Count (109/L)

Granulocyte Cell Count (109/L)

 

Δ

95% CI

AIC

Δ

95% CI

AIC

Men and Women

      

Critical Period Modelb

      

   Childhood

-0.13

(-0.19, -0.06)

8789

-0.09

(-0.14, -0.04)

3967

   Early Adult

-0.31*

(-0.38, -0.24)

8725

-0.23

(-0.29, -0.18)

3907

   Late Adult

-0.18*

(-0.27, -0.10)

8779

-0.16

(-0.22, -0.09)

3951

   Current

-0.18

(-0.25, -0.12)

8769

-0.15

(-0.20, -0.09)

3944

Accumulation Modelc

  

8722

  

3901

   0

0

  

0

  

   1

-0.17

(-0.27, -0.07)

 

-0.13

(-0.21, -0.05)

 

   2

-0.28

(-0.37, -0.18)

 

-0.21

(-0.28, -0.13)

 

   3

-0.42

(-0.52, -0.32)

 

-0.32

(-0.40, -0.24)

 

   4

-0.46

(-0.59, -0.32)

 

-0.37

(-0.47, -0.26)

 

Sensitive Periods Modeld

  

8713

  

3892

   Childhood

-0.06

(-0.13, 0.01)

 

-0.04

(-0.09, 0.02)

 

   Early Adult

-0.24

(-0.32, -0.17)

 

-0.18

(-0.24, -0.12)

 

   Late Adult

-0.08

(-0.16, 0.01)

 

-0.07

(-0.14, -0.01)

 

   Current

-0.10

(-0.18, -0.03)

 

-0.08

(-0.14, -0.02)

 

Fully Saturated Modele

  

8725

  

3907

  1. Abbreviations: CI Confidence Interval; AIC Akaike Information Criterion
  2. Bold numbers indicate P < 0.05 for coefficients or best fitting model for AICs * Test for interaction with sex significant at p < 0.05 level
  3. aAge in five year age groups. bEstimates for SEP at each individual life stage adjusted for age, sex, smoking, alcohol use, and physical activity but unadjusted for SEP at other life stages. cNumber of periods in high SEP adjusted for age, sex, smoking, alcohol use, and physical activity. dMutually adjusted for SEP at other life stages and adjusted for age, sex, smoking, alcohol use, and physical activity. eIncludes SEP at all four life stages and all possible interactions between all four measures of SEP. Also adjusted for age, sex, smoking, alcohol use, and physical activity