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Table 4 Associations of high socioeconomic position compared to low at four life stages with white cell count and granulocyte count, adjusted for agea, sex and lifestyle factors in 9,981 Chinese adults (≥50 years) from the Guangzhou Biobank Cohort Study, phase 3, 2006-2008

From: Life-course origins of social inequalities in adult immune cell markers of inflammation in a developing southern Chinese population: the Guangzhou Biobank Cohort Study

  White Blood Cell Count (109/L) Granulocyte Cell Count (109/L)
  Δ 95% CI AIC Δ 95% CI AIC
Men and Women       
Critical Period Modelb       
   Childhood -0.13 (-0.19, -0.06) 8789 -0.09 (-0.14, -0.04) 3967
   Early Adult -0.31* (-0.38, -0.24) 8725 -0.23 (-0.29, -0.18) 3907
   Late Adult -0.18* (-0.27, -0.10) 8779 -0.16 (-0.22, -0.09) 3951
   Current -0.18 (-0.25, -0.12) 8769 -0.15 (-0.20, -0.09) 3944
Accumulation Modelc    8722    3901
   0 0    0   
   1 -0.17 (-0.27, -0.07)   -0.13 (-0.21, -0.05)  
   2 -0.28 (-0.37, -0.18)   -0.21 (-0.28, -0.13)  
   3 -0.42 (-0.52, -0.32)   -0.32 (-0.40, -0.24)  
   4 -0.46 (-0.59, -0.32)   -0.37 (-0.47, -0.26)  
Sensitive Periods Modeld    8713    3892
   Childhood -0.06 (-0.13, 0.01)   -0.04 (-0.09, 0.02)  
   Early Adult -0.24 (-0.32, -0.17)   -0.18 (-0.24, -0.12)  
   Late Adult -0.08 (-0.16, 0.01)   -0.07 (-0.14, -0.01)  
   Current -0.10 (-0.18, -0.03)   -0.08 (-0.14, -0.02)  
Fully Saturated Modele    8725    3907
  1. Abbreviations: CI Confidence Interval; AIC Akaike Information Criterion
  2. Bold numbers indicate P < 0.05 for coefficients or best fitting model for AICs * Test for interaction with sex significant at p < 0.05 level
  3. aAge in five year age groups. bEstimates for SEP at each individual life stage adjusted for age, sex, smoking, alcohol use, and physical activity but unadjusted for SEP at other life stages. cNumber of periods in high SEP adjusted for age, sex, smoking, alcohol use, and physical activity. dMutually adjusted for SEP at other life stages and adjusted for age, sex, smoking, alcohol use, and physical activity. eIncludes SEP at all four life stages and all possible interactions between all four measures of SEP. Also adjusted for age, sex, smoking, alcohol use, and physical activity