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Table 5 Summary of community-based studies for case management with oral antibiotics for and effect on cause specific neonatal mortality due to pneumonia

From: Effect of case management on neonatal mortality due to sepsis and pneumonia

Ref and year

Country

Setting

Study design

Therapy given

Other interventions in package

Coverage of antibiotic case management (% of those who need it)

Intervention group (N/D)

Control group (N/D)

Effect size RR (95 % CI)

         

RR of Sepsis specific NMR

RR of Pneumonia specific NMR

Pandey 1991[16]

Nepal

Rural

Non randomized -concurrent control

Cotrimoxazole 4 mg/kg BD for 5 days. Chloramphenicol if no improvement

Maternal education, and 15% measles immunization coverage of children

<40-70% (estimates as per study PIs)

81/681

16/681

0.85

(0.65-1.12)

0.89

(0.46-1.72)

Mtango 1986[15]

Tanzania

Rural

Non randomized -concurrent control

Cotrimoxazole PO

Health education to mothers about symptoms & signs of ARI and referring severe cases to the next higher level of care.

<40-70% (estimates as per study PIs)

37/1638

7/1638

0.70

(0.47-1.07)

0.44

(0.18-1.07)

Khan 1990[14]

Pakistan

Rural

Non randomized -concurrent control

CotrimoxazolePO

Qualified nurses monitored and supervised CHW activities and with assistance of the CHWs, conducted frequent, informal, interactive health education programs

<40-70% (estimates as per study PIs)

26/2690

9/686

0.74

(0.35 - 1.57)

Did not report pneumonia specific mortality

Bang 1990[10]

India

Rural

Non randomized -concurrent control

Cotrimoxazole 2.5 ml twice daily for 7 days

Mass health education about childhood pneumonia

76% (for children <5)

104/1533

31/1533

0.70

(0.54-0.91)

0.52

(0.33-0.82)