Effects of vaccination and population structure on influenza epidemic spread in the presence of two circulating strains

Table 2 Total attack rates for 2-age class network model

		Attack rates: Prior vaccination V₀= 0.2, ω₀ = 0.0			Attack rates: Vaccination during epidemic: V₀= 0, ω₀ = 1.0
δ	T*	Strain 1+2	Strain 1	Strain 2	Strain 1+2	Strain 1	Strain 2
0.9	10	0.149929	0.229126	0.178316	0.141735	0.393720	0.083434
0.9	60	0.115638	0.279763	0.117244	0.000858	0.541612	0.000404
0.4	10	0.037663	0.338132	0.082410	0.008601	0.528141	0.010630
0.4	60	0.000463	0.398912	0.000749	0.000001	0.542568	0.000003

For the 2-age class network model, the initial strain-1 infection occurs in a fraction ε₁ = 0.5 of individuals in class (k₁,a₁) = (5,1), and initial strain-2 infection, occurs at time T* = 10 or 60 days later, in a fraction ε₂ = 0.5 of individuals in class (k₂,a₂) = (10,2). For these conditions, and the given degree- and age-distributions, the initial number of strain-1 and strain-2 infections (introduced at times t = 0 and T*, respectively) in a population of size N =10,000, is 67 and 12, respectively.

ISSN: 1471-2458