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Table 3 Fits to the Gaush & Smith (1968) single-cycle, single-history experiment (Figure 5) [9]

From: Exploring the effect of biological delays in kinetic models of influenza within a host or cell culture

Dista

Ï„ L (h)

σ L

Ï„ I (h)

σ I

(h)

(h)

SSR

AICc

exp

1.8 × 106

10.5

—

10.5

—

7.3

7.3

3.59

-21.3

δ

7.5 × 105

6.2

—

34.5

—

6.2

34.5

—b

—

N

5.4 × 106

12.4

4.6 h

0.17

9.7 h

12.4

6.6

0.79

-41.3

 

[1.4:8.7]c

[6.7:14.3]

[1.9:5.8]

[0.002:23]

[4.3:13.3]

    

lnN

2.0 × 106

8.5

0.49

18.2

0

8.5

18.2

0.93

-38.3

 

[1.0:4.6]

[5.4:10.8]

[0.24:0.58]

[9.6:25.6]

[0:0.41]

    
  1. a — Delay model used: exponential (exp), fixed (δ), normal (N), and lognormal (lnN).
  2. b — Using the fixed-delay model, virus titer is zero at all times prior to the appearance of infectious cells such that the SSR measured in log scale cannot be computed.
  3. c — 95% confidence intervals are given in brackets for the normal and lognormal fits.