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Table 2 Risk factors for relapse, failure, or default from initial TB treatment, a subgroup analysis.

From: Risk factors for tuberculosis treatment failure, default, or relapse and outcomes of retreatment in Morocco

Subgroup

Risk factor

Univariate analysis

(OR, 95% CI)

Multivariate analysis

(OR, 95% CI)

Relapse (N = 35)

   Lack of sputum smear conversion to negative by 3 months

4.58 (2.22-9.43)

4.14 (1.92-9.01)

   Missed doses during the intensive phase

3.23 (0.96-10.9)

NS

Treatment failure (N = 18)

   Lack of sputum smear conversion to negative by 3 months

**

**

   Comorbid conditions

3.29 (1.08-9.99)

NS

Treatment default (N = 27)

   Male gender

6.50 (1.51-28.1)

4.56 (0.96-20.7)

   Substance use†

4.19 (1.83-9.56)

2.73 (1.04-7.15)

   Missed doses during the intensive phase

12.9 (4.65-35.7)

10.9 (3.47-34.0)

   Hospitalization during treatment

2.56 (1.04-6.23)

3.84 (1.41-10.5)

  1. ** Three-month sputum smear conversion to negative was negative in all failure patients so could not be included in logistic regression models.
  2. †Tobacco, alcohol, or illicit drug use.