Estimated birth weight and adult cardiovascular risk factors in a developing southern Chinese population: a cross sectional study

Schooling, CM; Jiang, CQ; Lam, TH; Cowling, BJ; Au Yeung, SL; Zhang, WS; Cheng, KK; Leung, GM

doi:10.1186/1471-2458-10-270

Table 2 Instrumental variable estimate for the effect per birth weight standard deviation on cardiovascular disease risk factors in 18,958 older Chinese men and women in phases 2 and 3 of the Guangzhou Biobank Cohort Study (2005-8), overall and stratified by sex

From: Estimated birth weight and adult cardiovascular risk factors in a developing southern Chinese population: a cross sectional study

				All		Men		Women
¢Parameters	Men	Women	†Model	Δ	95%CI	Δ	95%CI	Δ	95%CI	¶p
SBP	131.8	126.7	1	-0.27	-0.55 to 0.009	-0.46	-1.01 to 0.08	-0.18	-0.50 to 0.15	0.41
(SD)	(21.1)	(21.7)	2	-0.29	-0.57 to -0.01	-0.46	-1.00 to 0.08	-0.23	-0.55 to 0.09	0.54
(mmHg)			3	-0.25	-0.53 to 0.03	-0.39	-0.93 to 0.15	-0.20	-0.52 to 0.12	0.59
			4	-0.24	-0.51 to 0.03	-0.45	-0.98 to 0.08	-0.17	-0.49 to 0.15	0.43
DBP	75.6	71.7	1	-0.35	-0.50 to -0.20	-0.54	-0.84 to -0.24	-0.28	-0.45 to -0.10	0.16
(SD)	(11.2)	(10.9)	2	-0.35	-0.50 to -0.20	-0.53	-0.83 to -0.23	-0.29	-0.47 to -0.12	0.21
(mmHg)			3	-0.33	-0.48 to -0.18	-0.51	-0.81 to -0.21	-0.27	-0.44 to -0.10	0.20
			4	-0.32	-0.47 to -0.18	-0.54	-0.83 to -0.26	-0.25	-0.42 to -0.08	0.11
FBG	5.6	5.6	1	0.007	-0.01 to 0.03	-0.02	-0.06 to 0.02	0.02	-0.007 to 0.04	0.10
(SD)	(1.6)	(1.6)	2	0.006	-0.01 to 0.03	-0.02	-0.06 to 0.02	0.02	-0.009 to 0.04	0.12
(mmol/L)			3	0.008	-0.01 to 0.03	-0.02	-0.06 to 0.02	0.02	-0.006 to 0.04	0.12
			4	0.009	-0.01 to 0.03	-0.02	-0.06 to 0.01	0.02	-0.004 to 0.04	0.08
TG	1.7	1.7	1	-0.008	-0.03 to 0.01	-0.03	-0.07 to 0.008	0.003	-0.02 to 0.02	0.10
(SD)	(1.4)	(1.3)	2	-0.007	-0.03 to 0.01	-0.03	-0.07 to 0.008	0.003	-0.02 to 0.02	0.11
(mmol/L)			3	-0.006	-0.02 to 0.01	-0.03	-0.07 to 0.007	0.004	-0.02 to 0.03	0.11
			4	-0.004	-0.02 to 0.01	-0.03	-0.07 to 0.003	0.007	-0.01 to 0.03	0.05
TC	5.6	6.1	1	0.01	-0.002 to 0.03	-0.005	-0.03 to 0.02	0.02	0.002 to 0.04	0.14
(SD)	(1.1)	(1.1)	2	0.01	-0.001 to 0.03	-0.005	-0.03 to 0.02	0.02	0.004 to 0.04	0.13
(mmol/L)			3	0.01	-0.003 to 0.03	-0.006	-0.04 to 0.02	0.02	0.002 to 0.04	0.14
			4	0.01	-0.003 to 0.03	-0.007	-0.04 to 0.02	0.02	0.002 to 0.04	0.12
HDL-C	1.5	1.7	1	0.006	-0.0002 to 0.01	-0.005	-0.02 to 0.006	0.009	0.002 to 0.02	0.03
(SD)	(0.4)	(0.4)	2	0.005	-0.0008 to 0.01	-0.005	-0.02 to 0.005	0.009	0.002 to 0.02	0.03
(mmol/L)			3	0.004	-0.002 to 0.01	-0.006	-0.02 to 0.005	0.008	0.001 to 0.01	0.03
			4	0.003	-0.002 to 0.009	-0.005	-0.01 to 0.005	0.006	-0.0005 to 0.01	0.07
WHR	0.9	0.8	1	-0.0004	-0.001 to 0.0005	0.0001	-0.002 to 0.002	-0.0006	-0.002 to 0.0005	0.49
(SD)	(0.06)	(0.07)	2	-0.0004	-0.001 to 0.0005	0.0002	-0.002 to 0.002	-0.0007	-0.002 to 0.0004	0.40
			3	-0.0002	-0.001 to 0.0007	0.0004	-0.001 to 0.002	-0.0004	-0.001 to 0.0006	0.38
BMI	23.5	23.8	1	-0.05	-0.09 to 0.002	0.008	-0.08 to 0.10	-0.06	-0.12 to -0.006	0.19
(SD)	(3.1)	(3.3)	2	-0.04	-0.09 to 0.007	0.01	-0.08 to 0.10	-0.06	-0.12 to -0.005	0.18
(kg/m²)			3	-0.04	-0.09 to 0.008	0.02	-0.07 to 0.10	-0.06	-0.12 to -0.005	0.15

†Model 1 adjusted for use of appropriate medication, study phase, age and where appropriate sex
Model 2 additionally adjusted for parental possessions and education
Model 3 additionally adjusted for number of offspring, leg length and seated height
Model 4 additionally adjusted for BMI and WHR
¢SBP: Systolic blood pressure; DBP: Diastolic blood pressure; FBG: Fasting blood glucose; TG: Triglycerides; TC: Total cholesterol; HDL-C: HDL-cholesterol; WHR: Waist hip ratio BMI: Body mass index
¶p value for interaction by sex

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