Health and economic impact of rotavirus vaccination in GAVI-eligible countries

Kim, Sun-Young; Sweet, Steve; Slichter, David; Goldie, Sue J

doi:10.1186/1471-2458-10-253

Table 3 Health outcomes of rotavirus vaccination in the GAVI-eligible countries

From: Health and economic impact of rotavirus vaccination in GAVI-eligible countries

Country	Base-case vaccine efficacy (adjusted for serotype distribution)			Vaccine efficacy based on SAGE recommendation
	Reduction in risk of severe rotavirus disease events	Rotavirus deaths averted (per 1000 vaccinated children)	DALYs averted	Reduction in risk of severe rotavirus disease events	Rotavirus deaths averted (per 1000 vaccinated children)	DALYs averted
AFR D
Angola	55%	14.2	176,385	35%	9.0	111,341
Benin	55%	6.7	42,644	35%	4.2	26,918
Burkina Faso	50%	8.6	92,836	35%	5.9	63,999
Cameroon	54%	6.6	67,042	35%	4.2	42,761
Chad	55%	9.8	76,358	35%	6.2	48,200
Comoros	55%	2.4	1,245	54%	2.3	1,221
Ghana	59%	3.7	44,965	35%	2.2	26,291
Guinea	55%	6.9	43,736	35%	4.3	27,608
Guinea-Bissau	50%	9.5	13,602	35%	6.5	9,366
Liberia	55%	12.1	38,173	35%	7.6	24,096
Madagascar	55%	5.2	68,520	35%	3.3	43,252
Mali	55%	11.1	110,369	35%	7.0	69,669
Mauritania	55%	5.7	10,359	35%	3.6	6,539
Niger	55%	14.4	160,612	35%	9.1	101,384
Nigeria	51%	7.7	733,421	35%	5.3	498,170
Sao Thome	55%	4.7	430	35%	3.0	272
Senegal	55%	5.8	45,473	35%	3.7	28,704
Sierra Leone	55%	15.9	62,305	35%	10.1	39,329
The Gambia	55%	4.0	4,250	35%	2.5	2,682
Togo	55%	5.0	21,192	35%	3.1	13,377
AFR E
Burundi	55%	9.3	67,442	35%	5.8	42,572
Central African Republic	55%	7.7	19,559	35%	4.8	12,346
Congo	55%	3.2	7,180	35%	2.0	4,532
Cote d'Ivoire	51%	7.6	85,210	35%	5.2	57,935
Democratic Republic of the Congo	55%	10.3	541,455	35%	6.5	341,786
Eritrea	55%	3.1	11,263	54%	3.0	11,045
Ethiopia	55%	7.8	443,905	35%	4.9	280,209
Kenya	55%	5.0	132,053	35%	3.1	83,357
Lesotho	55%	0.9	838	35%	0.6	529
Malawi	57%	8.6	81,905	35%	5.2	50,027
Mozambique	55%	6.8	90,101	35%	4.3	56,875
Rwanda	55%	9.9	75,890	35%	6.2	47,905
Tanzania	57%	5.5	146,305	35%	3.4	89,138
Uganda	55%	6.0	153,907	35%	3.8	97,151
Zambia	51%	7.8	56,160	35%	5.3	37,952
Zimbabwe	52%	3.6	21,407	35%	2.4	14,392
AMR A, B & D
Cuba	57%	0.0	63	54%	0.0	60
Guyana	57%	4.8	969	54%	4.6	923
Honduras	57%	1.7	6,710	54%	1.6	6,386
Bolivia	57%	2.6	12,692	54%	2.5	12,080
Haiti	57%	5.2	26,275	35%	3.2	16,098
Nicaragua	57%	1.2	3,384	54%	1.1	3,195
EMR D
Afghanistan	53%	12.5	254,469	35%	8.2	166,606
Djibouti	53%	5.4	2,234	35%	3.5	1,463
Pakistan	53%	3.5	315,915	35%	2.3	206,836
Somalia	55%	12.1	78,642	35%	7.7	49,641
Sudan	53%	2.9	65,913	35%	1.9	43,155
Yemen	53%	4.0	67,530	35%	2.6	44,213
EUR B & C
Armenia	59%	1.1	907	54%	1.0	834
Azerbaijan	59%	4.7	14,086	35%	2.8	8,329
Georgia	59%	1.7	1,471	54%	1.6	1,352
Kyrgyzstan	59%	3.3	7,922	54%	3.1	7,277
Tajikistan	59%	7.1	24,217	54%	6.5	22,246
Uzbekistan	59%	3.6	41,188	54%	3.3	37,836
Moldova	59%	0.2	159	54%	0.2	146
Ukraine	59%	0.1	590	54%	0.1	542
SEAR B & D
Indonesia	57%	2.3	187,993	54%	2.2	176,588
Korea, Democratic Republic	57%	2.1	12,982	54%	2.0	12,194
Sri Lanka	57%	0.6	3,424	54%	0.6	3,216
Timor Leste	57%	4.3	4,470	54%	4.1	4,199
Bangladesh	55%	3.4	231,585	54%	3.3	225,739
Bhutan	57%	3.8	858	54%	3.6	806
India	53%	3.6	1,777,110	54%	3.7	1,802,809
Myanmar	57%	4.9	79,028	35%	3.0	47,784
Nepal	58%	3.5	52,750	54%	3.2	48,998
WPR B
Cambodia	57%	8.6	63,250	35%	5.2	38,244
Kiribati	57%	4.9	118	54%	4.6	111
Lao People Democratic Republic	57%	4.6	14,067	54%	4.3	13,213
Mongolia	57%	2.6	2,316	54%	2.5	2,176
Papua New Guinea	57%	5.0	16,493	54%	4.7	15,492
Solomon Islands	57%	1.7	493	54%	1.6	463
Viet Nam	58%	0.8	26,089	54%	0.8	24,032

I$ = International dollars; DALY = Disability-adjusted life year; ICER = Incremental cost-effectiveness ratio.
AFR = African Region; EMR = Eastern Mediterranean Region; EUR = European Region; AMR = Region of the Americas; WPR = Western Pacific Region; SEAR = South-East Asian Region.

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